Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.V659E
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EGFR

NM_005228.5:p.V659E

Associated Papers

Favourable Prognostic Significance of HER2 Mutations in Canine Pulmonary Adenocarcinoma Following Surgical Resection.

Ichimata M et al.

Veterinary and Comparative Oncology, 2025

Trastuzumab deruxtecan for the treatment of metastatic non-small cell lung cancer harboring HER2 non-exon 19/20 mutations: four case reports.

Meng Y et al.

Frontiers in Immunology, 2025

Protein Expression, Amplification, and Mutation of HER2 Gene in Canine Primary Pulmonary Adenocarcinomas: Preliminary Results.

Brunetti B et al.

Animals : an Open Access Journal From Mdpi, 2024

Next-Generation Sequencing in Lung Cancers-A Single-Center Experience in Taiwan.

Lai WA et al.

Medicina (kaunas, Lithuania), 2024

38399524 (PubMed )
Supplement: medicina-60-00236-s001.zip › Supplementary_figures.pdf

Next generation sequencing and genomic mapping: towards precision molecular diagnosis of lung cancer in Morocco.

Morjani O et al.

The Pan African Medical Journal, 2024

BRCA1 and NORE1A Form a Her2/Ras Regulated Tumor Suppressor Complex Modulating Senescence.

Nelson N et al.

Cancers, 2023

Identification of Activating Mutations in the Transmembrane and Extracellular Domains of EGFR.

Wagner A et al.

Biochemistry, 2022

Genomic profiles and their associations with TMB, PD-L1 expression, and immune cell infiltration landscapes in synchronous multiple primary lung cancers.

Hu C et al.

Journal for Immunotherapy of Cancer, 2021

Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung cancer: Analysis of over 8000 cases.

Mack PC et al.

Cancer, 2020

Molecular features of lung adenocarcinoma in young patients.

Chen Z et al.

Bmc Cancer, 2019

Insight into the recognition patterns of the ErbB receptor family transmembrane domains: heterodimerization models through molecular dynamics search.

Samna Soumana O et al.

European Biophysics Journal : Ebj, 2008

ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner.

Ren Z et al.

The Journal of Biological Chemistry, 2002

Identification of a region within the ErbB2/HER2 intracellular domain that is necessary for ligand-independent association.

Penuel E et al.

The Journal of Biological Chemistry, 2002

Molecular modeling of c-erbB2 receptor dimerization: coiled-coil structure of wild and oncogenic transmembrane domains--stabilization by interhelical hydrogen bonds in the oncogenic form.

Garnier N et al.

Biopolymers, 1997

Detailed description of an alpha helix-->pi bulge transition detected by molecular dynamics simulations of the p185c-erbB2 V659G transmembrane domain.

Duneau JP et al.

Journal of Biomolecular Structure & Dynamics, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."