Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.N700D
Back to variants list

EGFR

NM_005228.5:p.N700D

Associated Papers

Next-Generation Sequencing Analysis of Mutations in Circulating Tumor DNA from the Plasma of Patients with Head-Neck Cancer Undergoing Chemo-Radiotherapy Using a Pan-Cancer Cell-Free Assay.

Koukourakis MI et al.

Current Oncology (toronto, Ont.), 2023

Durable response to afatinib in an advanced lung adenocarcinoma patient with an EGFR L858R/G729A compound mutation: a case report.

Wu L et al.

Annals of Translational Medicine, 2022

Colorectal adenocarcinoma-derived EGFR mutants are oncogenic and sensitive to EGFR-targeted monoclonal antibodies, cetuximab and panitumumab.

Kim N et al.

International Journal of Cancer, 2020

Heterogeneous Responses to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs) in Patients with Uncommon EGFR Mutations: New Insights and Future Perspectives in this Complex Clinical Scenario.

Russo A et al.

International Journal of Molecular Sciences, 2019

Multigene Mutation Profiling and Clinical Characteristics of Small-Cell Lung Cancer in Never-Smokers vs. Heavy Smokers (Geno1.3-CLICaP).

Cardona AF et al.

Frontiers in Oncology, 2019

Challenges of Providing Concordant Interpretation of Somatic Variants in Non-Small Cell Lung Cancer: A Multicenter Study.

Gao P et al.

Journal of Cancer, 2019

31205538 (PubMed )
Supplement: jcav10p1814s1.xls › Table_S10

Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors and Non-Small Cell Lung Cancer (NSCLC) - Advances in Molecular Diagnostic Techniques to Facilitate Targeted Therapy.

Ghafoor Q et al.

Pathology Oncology Research : Por, 2018

Epidermal growth factor receptor T790M mutation: A major culprit in the progression of epidermal growth factor receptor-driven non-small cell lung cancer and the role of repeat biopsy.

Aggarwal S et al.

Indian Journal of Cancer, 2017

BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.

Deihimi S et al.

Oncotarget, 2017

Discrimination of driver and passenger mutations in epidermal growth factor receptor in cancer.

Anoosha P et al.

Mutation Research, 2015

The impact of rare EGFR mutations on the treatment response of patients with non-small cell lung cancer.

Karachaliou N et al.

Expert Review of Respiratory Medicine, 2015

A systematic profile of clinical inhibitors responsive to EGFR somatic amino acid mutations in lung cancer: implication for the molecular mechanism of drug resistance and sensitivity.

Ai X et al.

Amino Acids, 2014

EGFR mutation status in brain metastases of non-small cell lung carcinoma.

Burel-Vandenbos F et al.

Journal of Neuro-oncology, 2013

The role of the molecular footprint of EGFR in tailoring treatment decisions in NSCLC.

Gately K et al.

Journal of Clinical Pathology, 2012

Effectiveness of tyrosine kinase inhibitors on "uncommon" epidermal growth factor receptor mutations of unknown clinical significance in non-small cell lung cancer.

Wu JY et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011

21531810 (PubMed )
Supplement: 10780432ccr103408-sup-ccr_10-3408_wu_t4.pdf

Consensus for EGFR mutation testing in non-small cell lung cancer: results from a European workshop.

Pirker R et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2010

Epidermal growth factor receptor mutations in lung cancer.

Sharma SV et al.

Nature Reviews. Cancer, 2007

Epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer: impact of primary or secondary mutations.

Sakurada A et al.

Clinical Lung Cancer, 2006

Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non-small cell lung cancer.

Chou TY et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2005

Epidermal growth factor receptor-activating mutation(E746_T751>VP) in pancreatic ductal adenocarcinoma responds to erlotinib, followed by epidermal growth factor receptor resistance-mediating mutation (A647T): A case report and literature review.

Patel GK et al.

Journal of Cancer Research and Therapeutics, 0

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."