Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.Q701L
Back to variants list

EGFR

NM_005228.5:p.Q701L

Associated Papers

Spatial multi-omics unveils the monoclonal origin, neuroendocrine plasticity, and microenvironment niches in combined small cell lung cancer.

Wang Z et al.

Biorxiv : the Preprint Server for Biology, 2026

Proteogenomic analysis of air-pollution-associated lung cancer reveals prevention and therapeutic opportunities.

Zhang H et al.

Elife, 2024

39432560 (PubMed )
Supplement: elife-95453-supp1.xlsx › S1c

Outcomes in non-small cell lung cancer with uncommon epidermal growth factor receptor L858 substitutions under first-line epidermal growth factor receptor tyrosine kinase inhibitors: A large real-world cohort study.

Shao Y et al.

Cancer Science, 2024

38932450 (PubMed )
Supplement: CAS-115-2751-s001.pdf

Rare mutation-dominant compound EGFR-positive NSCLC is associated with enriched kinase domain-resided variants of uncertain significance and poor clinical outcomes.

Zhao W et al.

Bmc Medicine, 2023

36829178 (PubMed )
Supplement: 12916_2023_2768_MOESM1_ESM.docx

Structure-Guided Strategies of Targeted Therapies for Patients with EGFR-Mutant Non-Small Cell Lung Cancer.

Du Z et al.

Biomolecules, 2023

36830579 (PubMed )
Supplement: biomolecules-13-00210-s001.zip › biomolecules-2098784-supplementary.xlsx › Table_S2

Multi-region exome sequencing reveals the intratumoral heterogeneity of surgically resected small cell lung cancer.

Zhou H et al.

Nature Communications, 2021

Multiple combination therapy based on intrathecal pemetrexed in non-small cell lung cancer patients with refractory leptomeningeal metastasis.

Miao Q et al.

Annals of Palliative Medicine, 2020

Impact and Diagnostic Gaps of Comprehensive Genomic Profiling in Real-World Clinical Practice.

Singh AP et al.

Cancers, 2020

Precision medicine and actionable alterations in lung cancer: A single institution experience.

Mambetsariev I et al.

Plos One, 2020

32045431 (PubMed )
Supplement: pone.0228188.s005.xlsx › Sheet1

Genomic Signature of Driver Genes Identified by Target Next-Generation Sequencing in Chinese Non-Small Cell Lung Cancer.

Wen S et al.

The Oncologist, 2019

Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations.

Ikemura S et al.

Proceedings of the National Academy of Sciences of the United States of America, 2019

31043566 (PubMed )
Supplement: pnas.1819430116.sapp.pdf

Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer.

Quan X et al.

Oncology Letters, 2018

Uncommon EGFR mutations in advanced non-small cell lung cancer.

O'Kane GM et al.

Lung Cancer (amsterdam, Netherlands), 2017

Lung adenocarcinoma patients of young age have lower EGFR mutation rate and poorer efficacy of EGFR tyrosine kinase inhibitors.

Wu SG et al.

Erj Open Research, 2017

Prediction and prioritization of neoantigens: integration of RNA sequencing data with whole-exome sequencing.

Karasaki T et al.

Cancer Science, 2017

27960040 (PubMed )
Supplement: CAS-108-170-s006.xlsx › Suppl_Table_3

Analysis of progression-free survival of first-line tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring leu858Arg or exon 19 deletions.

Kuan FC et al.

Oncotarget, 2017

27935868 (PubMed )
Supplement: oncotarget-08-1343-s001.pdf

Not all epidermal growth factor receptor mutations in lung cancer are created equal: Perspectives for individualized treatment strategy.

Kobayashi Y et al.

Cancer Science, 2016

EGFR Exon 18 Mutations in Lung Cancer: Molecular Predictors of Augmented Sensitivity to Afatinib or Neratinib as Compared with First- or Third-Generation TKIs.

Kobayashi Y et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2015

EGFR Exon 18 Mutations in East Asian Patients with Lung Adenocarcinomas: A Comprehensive Investigation of Prevalence, Clinicopathologic Characteristics and Prognosis.

Cheng C et al.

Scientific Reports, 2015

Impact of EGFR mutation detection methods on the efficacy of erlotinib in patients with advanced EGFR-wild type lung adenocarcinoma.

Tseng JS et al.

Plos One, 2014

25215536 (PubMed )
Supplement: pone.0107160.s004.pdf

Effectiveness of tyrosine kinase inhibitors on "uncommon" epidermal growth factor receptor mutations of unknown clinical significance in non-small cell lung cancer.

Wu JY et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."