Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.K714E
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EGFR

NM_005228.5:p.K714E

Associated Papers

First-line Osimertinib for Lung Cancer With Uncommon EGFR Exon 19 Mutations and EGFR Compound Mutations.

Cheunkarndee T et al.

Jto Clinical and Research Reports, 2024

Rare mutation-dominant compound EGFR-positive NSCLC is associated with enriched kinase domain-resided variants of uncertain significance and poor clinical outcomes.

Zhao W et al.

Bmc Medicine, 2023

36829178 (PubMed )
Supplement: 12916_2023_2768_MOESM1_ESM.docx

Structure-Guided Strategies of Targeted Therapies for Patients with EGFR-Mutant Non-Small Cell Lung Cancer.

Du Z et al.

Biomolecules, 2023

36830579 (PubMed )
Supplement: biomolecules-13-00210-s001.zip › biomolecules-2098784-supplementary.xlsx › Table_S8

Next-Generation Sequencing Reveals High Uncommon EGFR Mutations and Tumour Mutation Burden in a Subgroup of Lung Cancer Patients.

Guo G et al.

Frontiers in Oncology, 2021

Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations.

Ikemura S et al.

Proceedings of the National Academy of Sciences of the United States of America, 2019

31043566 (PubMed )
Supplement: pnas.1819430116.sapp.pdf

Significant Improvement in Detecting BRAF, KRAS, and EGFR Mutations Using Next-Generation Sequencing as Compared with FDA-Cleared Kits.

Ma W et al.

Molecular Diagnosis & Therapy, 2017

Prevalence of EGFR Mutations in Lung Cancer in Uruguayan Population.

Berois N et al.

Journal of Cancer Epidemiology, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."