Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.L747del1
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EGFR

NM_005228.5:p.L747del1

Associated Papers

Brief Report: The Effectiveness of Osimertinib in Advanced Nonsmall Cell Lung Cancer Harboring Various EGFR Exon 19 Mutation Variants.

Chang LC et al.

Clinical Lung Cancer, 2025

Patients with Advanced Non-Small Cell Lung Cancer and the EGFR Exon 19 Deletion p.L747 Benefit from Chemotherapy and First-Generation Tyrosine Kinase Inhibitors Compared with Patients with p.E746.

Guan M et al.

Oncotargets and Therapy, 2025

RELAY, Erlotinib Plus Ramucirumab in Untreated, EGFR-Mutated, Metastatic NSCLC: Outcomes by EGFR Exon 19 Deletion Variants.

Nishino K et al.

Jto Clinical and Research Reports, 2024

Efficacy of Osimertinib in Patients with Lung Cancer Positive for Uncommon EGFR Exon 19 Deletion Mutations.

Grant MJ et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2023

Impact of EGFR exon 19 deletion subtypes on clinical outcomes in EGFR-TKI-Treated advanced non-small-cell lung cancer.

Huang LT et al.

Lung Cancer (amsterdam, Netherlands), 2022

Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Ikeuchi H et al.

Oncogene, 2022

35304574 (PubMed )
Supplement: 41388_2022_2263_MOESM5_ESM.xlsx › Supplementary_Table_4

Comutation and exclusion analysis in human tumors: A tool for cancer biology studies and for rational selection of multitargeted therapeutic approaches.

Ochoa S et al.

Human Mutation, 2019

Quantitative detection of EGFR mutations in circulating tumor DNA derived from lung adenocarcinomas.

Taniguchi K et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."