Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.E746_A750delins
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EGFR

NM_005228.5:p.E746_A750delins

Associated Papers

Prevalence of EGFR gene mutations in patients with early-stage resectable non-small cell lung cancer in Spain: the ORIGEN study.

Varela M et al.

Translational Lung Cancer Research, 2025

40386732 (PubMed )
Supplement: tlcr-14-04-1254-supplementary.pdf

Detection of Overlooked Rare EGFR Mutations in Non-small Cell Lung Cancer Using Multigene Testing.

Shiraishi N et al.

Thoracic Cancer, 2025

The relevance of the reference range for EGFR testing in non-small cell lung cancer patients.

Pisapia P et al.

Lung Cancer (amsterdam, Netherlands), 2024

The Advantage of Targeted Next-Generation Sequencing over qPCR in Testing for Druggable EGFR Variants in Non-Small-Cell Lung Cancer.

Szpechcinski A et al.

International Journal of Molecular Sciences, 2024

39063150 (PubMed )
Supplement: ijms-25-07908-s001.zip › ijms-3103240-supplementary.pdf

Evaluation of the Idylla™ EGFR Mutation Test on formalin-fixed, paraffin-embedded tissue of human lung cancer.

Xu Y et al.

Journal of Thoracic Disease, 2024

Simulation analysis of EGFR mutation detection: Oncomine Dx target test and AmoyDx panel impact on lung cancer treatment decisions.

Hirotsu Y et al.

Scientific Reports, 2024

38238401 (PubMed )
Supplement: 41598_2024_52006_MOESM5_ESM.xlsx › combie_list

Clinical Validation of the Unparalleled Sensitivity of the Novel Allele-Discriminating Priming System Technology-Based EGFR Mutation Assay in Patients with Operable Non-Small Cell Lung Cancer.

Park IH et al.

Cancer Research and Treatment, 2024

37340844 (PubMed )
Supplement: crt-2023-408_S1_Table.pdf

Next generation sequencing and genomic mapping: towards precision molecular diagnosis of lung cancer in Morocco.

Morjani O et al.

The Pan African Medical Journal, 2024

Comparison and Validation of Rapid Molecular Testing Methods for Theranostic Epidermal Growth Factor Receptor Alterations in Lung Cancer: Idylla versus Digital Droplet PCR.

Léonce C et al.

International Journal of Molecular Sciences, 2023

Clinical importance of the range of detectable variants between the Oncomine Dx target test and a conventional single-gene test for EGFR mutation.

Sakaguchi T et al.

Scientific Reports, 2023

37612335 (PubMed )
Supplement: 41598_2023_40271_MOESM1_ESM.pdf

Comparison between Three Different Techniques for the Detection of EGFR Mutations in Liquid Biopsies of Patients with Advanced Stage Lung Adenocarcinoma.

Casula M et al.

International Journal of Molecular Sciences, 2023

37047382 (PubMed )
Supplement: ijms-24-06410-s001.zip › ijms-2177723-supplementary.pdf

Relationship between driver gene mutations and clinical pathological characteristics in older lung adenocarcinoma.

Liu X et al.

Frontiers in Oncology, 2023

38023198 (PubMed )
Supplement: Table_1.xlsx › Table_S2

Utility of ctDNA Liquid Biopsies from Cancer Patients: An Institutional Study of 285 ctDNA Samples.

Gumà J et al.

Cancers, 2022

36497340 (PubMed )
Supplement: cancers-14-05859-s001.zip › cancers-2069645-supplementary.pdf

Utility of Select Gene Mutation Detection in Tumors by the Idylla Rapid Multiplex PCR Platform in Comparison to Next-Generation Sequencing.

Nkosi D et al.

Genes, 2022

35627184 (PubMed )
Supplement: genes-13-00799-s001.zip › genes-1613678-supplementary.pdf

PEAC: An Ultrasensitive and Cost-Effective MRD Detection System in Non-small Cell Lung Cancer Using Plasma Specimen.

Xu J et al.

Frontiers in Medicine, 2022

35308511 (PubMed )
Supplement: Table_1.XLSX › Sheet1

Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Shen F et al.

Frontiers in Oncology, 2022

35814426 (PubMed )
Supplement: DataSheet_1.xlsx › Table_S2

Evaluation of the Idylla ctEGFR mutation assay to detect EGFR mutations in plasma from patients with non-small cell lung cancers.

Gilson P et al.

Scientific Reports, 2021

34006948 (PubMed )
Supplement: 41598_2021_90091_MOESM2_ESM.pdf

EGFR-Mutated Squamous Cell Lung Cancer and Its Association With Outcomes.

Jin R et al.

Frontiers in Oncology, 2021

34195081 (PubMed )
Supplement: Table_2.xlsx › EGFR-Mutant_SCC

Ultrarapid EGFR Mutation Screening Followed by Comprehensive Next-Generation Sequencing: A Feasible, Informative Approach for Lung Carcinoma Cytology Specimens With a High Success Rate.

Arcila ME et al.

Jto Clinical and Research Reports, 2020

33511359 (PubMed )
Supplement: mmc1.docx

Rapid EGFR mutation testing in lung cancer tissue samples using a fully automated system and single-use cartridge.

Al-Turkmani MR et al.

Practical Laboratory Medicine, 2020

Multicenter Evaluation of the Fully Automated PCR-Based Idylla EGFR Mutation Assay on Formalin-Fixed, Paraffin-Embedded Tissue of Human Lung Cancer.

Evrard SM et al.

The Journal of Molecular Diagnostics : Jmd, 2019

Development, Implementation and Assessment of Molecular Diagnostics by Next Generation Sequencing in Personalized Treatment of Cancer: Experience of a Public Reference Healthcare Hospital.

Simarro J et al.

Cancers, 2019

31426418 (PubMed )
Supplement: cancers-11-01196-s001.pdf

Heterogeneous mutation pattern in tumor tissue and circulating tumor DNA warrants parallel NGS panel testing.

Guo Q et al.

Molecular Cancer, 2018

30153823 (PubMed )
Supplement: 12943_2018_875_MOESM5_ESM.xlsx › Table_S4_Tissue_DNA_Mutation

Clinical mutational profiling of 1006 lung cancers by next generation sequencing.

Illei PB et al.

Oncotarget, 2017

A primer and probe set for detecting multiple types of EGFR exon 19 deletions.

Chen TL et al.

Analytical Biochemistry, 2016

Epidemiology of doublet/multiplet mutations in lung cancers: evidence that a subset arises by chronocoordinate events.

Chen Z et al.

Plos One, 2008

19005564 (PubMed )
Supplement: pone.0003714.s003.xls › Table_S-1

Database of somatic mutations in EGFR with analyses revealing indel hotspots but no smoking-associated signature.

Gu D et al.

Human Mutation, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."