Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.L747delins
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EGFR

NM_005228.5:p.L747delins

Associated Papers

Detection of actionable mutations in circulating tumor DNA for non-small cell lung cancer patients.

van der Leest P et al.

Communications Medicine, 2025

40437208 (PubMed )
Supplement: 43856_2025_921_MOESM4_ESM.xlsx › Blad1

Distribution of EGFR and KRAS Mutations in Patients with Surgically Resected Non-Small Cell Lung Cancer from Southern Italy: Real-Life Data from a Single Institution and Literature Review.

Piazzolla M et al.

Cancers, 2025

40075579 (PubMed )
Supplement: cancers-17-00730-s001.zip › cancers-3468545-supplementary.xlsx › EGFRmutated_profile_SupplTab2

Atypical Droplet Digital Polymerase Chain Reaction Patterns That Indicate Uncommon but Clinically Actionable EGFR Mutations in Lung Cancer.

Lechner A et al.

Archives of Pathology & Laboratory Medicine, 2024

Comparison and Validation of Rapid Molecular Testing Methods for Theranostic Epidermal Growth Factor Receptor Alterations in Lung Cancer: Idylla versus Digital Droplet PCR.

Léonce C et al.

International Journal of Molecular Sciences, 2023

FACILITATE: A real-world, multicenter, prospective study investigating the utility of a rapid, fully automated real-time PCR assay versus local reference methods for detecting epidermal growth factor receptor variants in NSCLC.

Behnke A et al.

Pathology Oncology Research : Por, 2023

ERBB family fusions are recurrent and actionable oncogenic targets across cancer types.

Schubert L et al.

Frontiers in Oncology, 2023

37168365 (PubMed )
Supplement: Table_3.xlsx › EGFR_mutations

Relationship between driver gene mutations and clinical pathological characteristics in older lung adenocarcinoma.

Liu X et al.

Frontiers in Oncology, 2023

38023198 (PubMed )
Supplement: Table_1.xlsx › Table_S2

Molecular Divergence upon EGFR-TKI Resistance Could Be Dependent on the Exon Location of the Original EGFR-Sensitizing Mutation.

Serna-Blasco R et al.

Cancers, 2022

36139605 (PubMed )
Supplement: cancers-14-04446-s001.zip › Supplemental_data_S4.xlsx › variants_datasheet

Rapid EGFR evaluation from used H&E, IHC and FISH diagnostic slides with the Idylla platform.

Nunnari J et al.

Journal of Clinical Pathology, 2022

Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Shen F et al.

Frontiers in Oncology, 2022

35814426 (PubMed )
Supplement: DataSheet_1.xlsx › Table_S2

Case Report: Dacomitinib is effective in lung adenocarcinoma with rare EGFR mutation L747P and brain metastases.

Li Y et al.

Frontiers in Oncology, 2022

Mismatch Repair Deficiency and Somatic Mutations in Human Sinonasal Tumors.

Hieggelke L et al.

Cancers, 2021

34885191 (PubMed )
Supplement: cancers-13-06081-s001.zip › Table_S3_Targeted_panel_sequencing_result_of_sinonasal_tumor_cohort.pdf

Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity.

Yoshizawa T et al.

Npj Precision Oncology, 2021

33863983 (PubMed )
Supplement: 41698_2021_170_MOESM4_ESM.xlsx › Pre_Post_Afatinibshared_variant

Standardization of Somatic Variant Classifications in Solid and Haematological Tumours by a Two-Level Approach of Biological and Clinical Classes: An Initiative of the Belgian ComPerMed Expert Panel.

Froyen G et al.

Cancers, 2019

Oncologist uptake of comprehensive genomic profile guided targeted therapy.

Nesline MK et al.

Oncotarget, 2019

31384390 (PubMed )
Supplement: oncotarget-10-4616-s003.xlsx › TblS2TargetedTherapyDecisions

Real-time PCR and targeted next-generation sequencing in the detection of low level EGFR mutations: Instructive case analyses.

Cheng YW et al.

Respiratory Medicine Case Reports, 2019

Picoliter-Droplet Digital Polymerase Chain Reaction-Based Analysis of Cell-Free Plasma DNA to Assess EGFR Mutations in Lung Adenocarcinoma That Confer Resistance to Tyrosine-Kinase Inhibitors.

Seki Y et al.

The Oncologist, 2016

A cautionary lesson on the use of targeted methods for EGFR mutation analysis: a case report.

Walsh K et al.

Journal of Clinical Pathology, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."