Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.E749K
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EGFR

NM_005228.5:p.E749K

Associated Papers

Molecular profiling of solid tumors by next-generation sequencing: an experience from a clinical laboratory.

Bhai P et al.

Frontiers in Oncology, 2023

37483495 (PubMed )
Supplement: Table_6.xlsx › Comprehensive_panel

Predicting osimertinib-treatment outcomes through EGFR mutant-fraction monitoring in the circulating tumor DNA of EGFR T790M-positive patients with non-small cell lung cancer (WJOG8815L).

Sakai K et al.

Molecular Oncology, 2021

33131198 (PubMed )
Supplement: MOL2-15-126-s007.xlsx › Table_S3

Analytical Validation of a Hybrid Capture-Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA.

Clark TA et al.

The Journal of Molecular Diagnostics : Jmd, 2018

29936259 (PubMed )
Supplement: mmc12.xlsx › Table_S12

Molecular spectrum of somatic EGFR and KRAS gene mutations in non small cell lung carcinoma: determination of frequency, distribution pattern and identification of novel variations in Indian patients.

Das BR et al.

Pathology Oncology Research : Por, 2015

Mutations in epidermal growth factor receptor and K-ras in Chinese patients with colorectal cancer.

Yunxia Z et al.

Bmc Medical Genetics, 2010

Functional analysis of epidermal growth factor receptor (EGFR) mutations and potential implications for EGFR targeted therapy.

Kancha RK et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2009

Mutations of epidermal growth factor receptor in colon cancer indicate susceptibility or resistance to gefitinib.

Zhang X et al.

Oncology Reports, 2008

The epidermal growth factor receptor gene sequence is highly conserved in primary gastric cancers.

Mimori K et al.

Journal of Surgical Oncology, 2006

Somatic mutations of epidermal growth factor receptor in colorectal carcinoma.

Nagahara H et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."