Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.E749Q
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EGFR

NM_005228.5:p.E749Q

Associated Papers

Structure-Guided Strategies of Targeted Therapies for Patients with EGFR-Mutant Non-Small Cell Lung Cancer.

Du Z et al.

Biomolecules, 2023

36830579 (PubMed )
Supplement: biomolecules-13-00210-s001.zip › biomolecules-2098784-supplementary.xlsx › Table_S8

Longitudinal multi-gene panel assessment of circulating tumor DNA revealed tumor burden and molecular characteristics along treatment course of non-small cell lung cancer.

Ho GYF et al.

Translational Lung Cancer Research, 2020

Next‑generation sequencing‑based detection of EGFR, KRAS, BRAF, NRAS, PIK3CA, Her‑2 and TP53 mutations in patients with non‑small cell lung cancer.

Jing C et al.

Molecular Medicine Reports, 2018

Epidermal Growth Factor Receptor (EGFR) Mutation in Exon 19 (p.E749Q) Confers Resistance to Gefitinib in One Patient With Lung Adenocarcinoma.

Genestreti G et al.

Clinical Lung Cancer, 2017

Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Kim EY et al.

Cancer Biology & Therapy, 2016

ErbB polymorphisms: insights and implications for response to targeted cancer therapeutics.

Alaoui-Jamali MA et al.

Frontiers in Genetics, 2015

25699077 (PubMed )
Supplement: Table1.PDF

Somatic mutations of the epidermal growth factor receptor and non-small-cell lung cancer.

Zhang X et al.

Journal of Medical Genetics, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."