Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.A755D
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EGFR

NM_005228.5:p.A755D

Associated Papers

An in-depth exploration of four heterogeneity structure-based EGFR mutation subgroups in Chinese non-small cell lung cancer.

Yu Y et al.

Bmc Pulmonary Medicine, 2025

40611150 (PubMed )
Supplement: 12890_2025_3774_MOESM1_ESM.xlsx › Sheet1

Molecular profile of driver genes in lung adenocarcinomas of Brazilian patients who have never smoked: implications for targeted therapies.

Cavagna RO et al.

The Oncologist, 2024

38944844 (PubMed )
Supplement: oyae129_suppl_supplementary_table_2.xlsx › Supplementary_Table_1

The biomarkers ATLAS: An audit on 1100 non-small cell lung cancer from an Italian knowledge-based database.

Malapelle U et al.

Lung Cancer (amsterdam, Netherlands), 2024

Structure-Guided Strategies of Targeted Therapies for Patients with EGFR-Mutant Non-Small Cell Lung Cancer.

Du Z et al.

Biomolecules, 2023

36830579 (PubMed )
Supplement: biomolecules-13-00210-s001.zip › biomolecules-2098784-supplementary.xlsx › Table_S1

Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Ikeuchi H et al.

Oncogene, 2022

35304574 (PubMed )
Supplement: 41388_2022_2263_MOESM5_ESM.xlsx › Supplementary_Table_4

Structure-based classification predicts drug response in EGFR-mutant NSCLC.

Robichaux JP et al.

Nature, 2021

34526717 (PubMed )
Supplement: 41586_2021_3898_MOESM1_ESM.pdf

Co-occurring genetic alterations and primary EGFR T790M mutations detected by NGS in pre-TKI-treated NSCLCs.

Tang Y et al.

Journal of Cancer Research and Clinical Oncology, 2020

Genomic Signature of Driver Genes Identified by Target Next-Generation Sequencing in Chinese Non-Small Cell Lung Cancer.

Wen S et al.

The Oncologist, 2019

The percentage of Epidermal Growth Factor Receptor (EGFR)-mutated neoplastic cells correlates to response to tyrosine kinase inhibitors in lung adenocarcinoma.

de Biase D et al.

Plos One, 2017

Diamond: immunohistochemistry versus sequencing in EGFR analysis of lung adenocarcinomas.

Ragazzi M et al.

Journal of Clinical Pathology, 2016

Clinical Validation and Implementation of a Targeted Next-Generation Sequencing Assay to Detect Somatic Variants in Non-Small Cell Lung, Melanoma, and Gastrointestinal Malignancies.

Fisher KE et al.

The Journal of Molecular Diagnostics : Jmd, 2016

Utility of different massive parallel sequencing platforms for mutation profiling in clinical samples and identification of pitfalls using FFPE tissue.

Fassunke J et al.

International Journal of Molecular Medicine, 2015

Rare and complex mutations of epidermal growth factor receptor, and efficacy of tyrosine kinase inhibitor in patients with non-small cell lung cancer.

Keam B et al.

International Journal of Clinical Oncology, 2014

Molecular diagnostic profiling of lung cancer specimens with a semiconductor-based massive parallel sequencing approach: feasibility, costs, and performance compared with conventional sequencing.

Endris V et al.

The Journal of Molecular Diagnostics : Jmd, 2013

Complex mutations & subpopulations of deletions at exon 19 of EGFR in NSCLC revealed by next generation sequencing: potential clinical implications.

Marchetti A et al.

Plos One, 2012

22848739 (PubMed )
Supplement: pone.0042164.s003.xls › Table_S2

Correlation of EGFR mutations with chromosomal alterations and expression of EGFR, ErbB3 and VEGF in tumor samples of lung adenocarcinoma patients.

Reinmuth N et al.

Lung Cancer (amsterdam, Netherlands), 2008

Detection of epidermal growth factor receptor gene mutations in cytology specimens from patients with non-small cell lung cancer utilising high-resolution melting amplicon analysis.

Smith GD et al.

Journal of Clinical Pathology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."