Associated Papers
Altered conformational landscape and dimerization dependency underpins the activation of EGFR by αC-β4 loop insertion mutations.
Ruan Z et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018
Computational and Experimental Characterization of Patient Derived Mutations Reveal an Unusual Mode of Regulatory Spine Assembly and Drug Sensitivity in EGFR Kinase.
Ruan Z et al.
Biochemistry, 2017
Constitutive asymmetric dimerization drives oncogenic activation of epidermal growth factor receptor carboxyl-terminal deletion mutants.
Park AK et al.
Oncotarget, 2015
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