Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.A763V
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EGFR

NM_005228.5:p.A763V

Associated Papers

The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma.

Karachaliou GS et al.

Bmc Cancer, 2022

34986841 (PubMed )
Supplement: 12885_2021_8908_MOESM2_ESM.xlsx › APC_CTNNB1_wild_type

DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression.

Mäki-Nevala S et al.

Ebiomedicine, 2019

30578081 (PubMed )
Supplement: mmc1.pdf

Coexistence of EGFR, KRAS, BRAF, and PIK3CA Mutations and ALK Rearrangement in a Comprehensive Cohort of 326 Consecutive Spanish Nonsquamous NSCLC Patients.

Martín Martorell P et al.

Clinical Lung Cancer, 2017

Uncommon EGFR mutations in advanced non-small cell lung cancer.

O'Kane GM et al.

Lung Cancer (amsterdam, Netherlands), 2017

Examining Treatment Outcomes with Erlotinib in Patients with Advanced Non-Small Cell Lung Cancer Whose Tumors Harbor Uncommon EGFR Mutations.

Klughammer B et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2016

Efficacy of gefitinib or erlotinib in patients with squamous cell lung cancer.

Song Z et al.

Archives of Medical Science : Ams, 2015

A systematic profile of clinical inhibitors responsive to EGFR somatic amino acid mutations in lung cancer: implication for the molecular mechanism of drug resistance and sensitivity.

Ai X et al.

Amino Acids, 2014

A novel point mutation in exon 20 of EGFR showed sensitivity to erlotinib.

Xing K et al.

Medical Oncology (northwood, London, England), 2014

DNA-Mutation Inventory to Refine and Enhance Cancer Treatment (DIRECT): a catalog of clinically relevant cancer mutations to enable genome-directed anticancer therapy.

Yeh P et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2013

Efficacy of gefitinib for non-adenocarcinoma non-small-cell lung cancer patients harboring epidermal growth factor receptor mutations: a pooled analysis of published reports.

Shukuya T et al.

Cancer Science, 2011

Lung cancer with epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib treatment response.

Wu JY et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2008

[Mutations in the epidermal growth factor receptor: structure and biological function in human tumors].

Pedersen MW et al.

Ugeskrift for Laeger, 2006

Epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer: impact of primary or secondary mutations.

Sakurada A et al.

Clinical Lung Cancer, 2006

Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non-small cell lung cancer.

Chou TY et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."