Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.M766V
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EGFR

NM_005228.5:p.M766V

Associated Papers

Comprehensive mutational scanning of EGFR reveals TKI sensitivities of extracellular domain mutants.

Hayes TK et al.

Nature Communications, 2024

38548752 (PubMed )
Supplement: 41467_2024_45594_MOESM4_ESM.xlsx › All

Effects of Single Nucleotide Polymorphisms on the Binding of Afatinib to EGFR: A Potential Patient Stratification Factor Revealed by Modeling Studies.

Kannan S et al.

Journal of Chemical Information and Modeling, 2019

Computational and Experimental Characterization of Patient Derived Mutations Reveal an Unusual Mode of Regulatory Spine Assembly and Drug Sensitivity in EGFR Kinase.

Ruan Z et al.

Biochemistry, 2017

Comparison of the EGFR resistance mutation profiles generated by EGFR-targeted tyrosine kinase inhibitors and the impact of drug combinations.

Avizienyte E et al.

The Biochemical Journal, 2008

18588508 (PubMed )
Supplement: supplement_1.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."