Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.S768N
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EGFR

NM_005228.5:p.S768N

Associated Papers

Multimodal scanning of genetic variants with base and prime editing.

Belli O et al.

Nature Biotechnology, 2025

A molecular dynamics protocol for rapid prediction of EGFR overactivation and its application to the rare mutations S768I, S768N, D761N.

Behn J et al.

Computational and Structural Biotechnology Journal, 2025

Landscape of Clinically Relevant Genomic Alterations in the Indian Non-small Cell Lung Cancer Patients.

Jha P et al.

Clinical Lung Cancer, 2024

A real-world cohort study of first-line afatinib in patients with EGFR-mutant advanced non-small cell lung cancer in Vietnam.

Pham CP et al.

Bmc Cancer, 2024

38317094 (PubMed )
Supplement: 12885_2024_11891_MOESM1_ESM.xlsx › Sheet1

EGFR Mutation Detection in Brazilian Patients With Non-Small-Cell Lung Cancer: Lessons From Real-World Data Scenario of Molecular Testing.

Montella T et al.

Jco Global Oncology, 2023

Structure-Guided Strategies of Targeted Therapies for Patients with EGFR-Mutant Non-Small Cell Lung Cancer.

Du Z et al.

Biomolecules, 2023

Somatic mutation detection and KRAS amplification in testicular germ cell tumors.

Cabral ERM et al.

Frontiers in Oncology, 2023

Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

Chevrier S et al.

International Journal of Molecular Medicine, 2022

35244186 (PubMed )
Supplement: Supplementary_Data2.xlsx › Feuil1

Proof-of-Concept Pilot Study on Comprehensive Spatiotemporal Intra-Patient Heterogeneity for Colorectal Cancer With Liver Metastasis.

Kyrochristos ID et al.

Frontiers in Oncology, 2022

35402285 (PubMed )
Supplement: Table_1.xlsx › Patient_plots

Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg-like Cells, and Common EGFR Somatic Mutations.

Monteagudo C et al.

The American Journal of Surgical Pathology, 2021

Presentation of EGFR mutations in 162 family probands with multiple primary lung cancer.

Li C et al.

Translational Lung Cancer Research, 2021

Plasma or Serum: Which Is Preferable for Mutation Detection in Liquid Biopsy?

Pittella-Silva F et al.

Clinical Chemistry, 2020

EGFR and KRAS mutations in lung carcinomas in the Dutch population: increased EGFR mutation frequency in malignant pleural effusion of lung adenocarcinoma.

Smits AJ et al.

Cellular Oncology (dordrecht, Netherlands), 2012

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

Characterization of epidermal growth factor receptor mutations in non-small-cell lung cancer patients of African-American ancestry.

Harada T et al.

Oncogene, 2011

Co-conserved features associated with cis regulation of ErbB tyrosine kinases.

Mirza A et al.

Plos One, 2010

Genetic abnormalities of the EGFR pathway in African American Patients with non-small-cell lung cancer.

Leidner RS et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."