Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.V774A
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EGFR

NM_005228.5:p.V774A

Associated Papers

Current paradigm of EGFRins20 in non-small cell lung cancer: A long way forward.

Miyamura BV et al.

Med (new York, N.y.), 2025

Resistance Mutation Profiles Associated with Current Treatments for Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer in the United States: A Systematic Literature Review.

Vadagam P et al.

Current Oncology (toronto, Ont.), 2025

40277748 (PubMed )
Supplement: curroncol-32-00191-s001.zip › curroncol-3409061-supplementary.pdf

Whole-Exome Sequencing Reveals Novel Candidate Driver Mutations and Potential Druggable Mutations in Patients with High-Risk Neuroblastoma.

Nokchan N et al.

Journal of Personalized Medicine, 2024

39338204 (PubMed )
Supplement: jpm-14-00950-s001.zip › Supplementary_Table_S5.xlsx › Supplementary_Table_S5.

Resistance mechanisms of EGFR tyrosine kinase inhibitors, in EGFR exon 20 insertion-mutant lung cancer.

Park S et al.

European Journal of Cancer (oxford, England : 1990), 2024

Simulation analysis of EGFR mutation detection: Oncomine Dx target test and AmoyDx panel impact on lung cancer treatment decisions.

Hirotsu Y et al.

Scientific Reports, 2024

38238401 (PubMed )
Supplement: 41598_2024_52006_MOESM6_ESM.xlsx › 01-Mar-2023-ClinicalEvidenceSum

EGFR exon20 insertion mutations in non-small cell lung cancer: Clinical implications and recent advances in targeted therapies.

Bai Q et al.

Cancer Treatment Reviews, 2023

Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity.

Elamin YY et al.

Cancer Cell, 2022

Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

G V et al.

Frontiers in Genetics, 2022

36561320 (PubMed )
Supplement: Table3.xlsx › Sheet1

Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis.

Cowan RW et al.

Clinical and Translational Gastroenterology, 2021

34797250 (PubMed )
Supplement: ct9-12-e00431-s005.xlsx › SDC5

Targeting EGFR Exon 20 Insertions in Non-Small Cell Lung Cancer: Recent Advances and Clinical Updates.

Meador CB et al.

Cancer Discovery, 2021

Tackling Drug Resistance in EGFR Exon 20 Insertion Mutant Lung Cancer.

Pacini L et al.

Pharmacogenomics and Personalized Medicine, 2021

EGFR exon 20 insertions in advanced non-small cell lung cancer: A new history begins.

Remon J et al.

Cancer Treatment Reviews, 2020

Uncommon EGFR Mutations in Non-Small Cell Lung Cancer and Their Impact on the Treatment.

Bílek O et al.

Klinicka Onkologie : Casopis Ceske a Slovenske Onkologicke Spolecnosti, 2019

Uncommon EGFR mutations in advanced non-small cell lung cancer.

O'Kane GM et al.

Lung Cancer (amsterdam, Netherlands), 2017

Drug-sensitive FGFR3 mutations in lung adenocarcinoma.

Chandrani P et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2017

27998968 (PubMed )
Supplement: mdw636_supp.zip › Chandrani_et_al._suppl_tables_20161110.xlsx › S3.Variants

Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations-a review.

Stewart EL et al.

Translational Lung Cancer Research, 2015

A novel point mutation in exon 20 of EGFR showed sensitivity to erlotinib.

Xing K et al.

Medical Oncology (northwood, London, England), 2014

EGFR mutations as a prognostic and predictive marker in non-small-cell lung cancer.

Fang S et al.

Drug Design, Development and Therapy, 2014

Effectiveness of tyrosine kinase inhibitors on "uncommon" epidermal growth factor receptor mutations of unknown clinical significance in non-small cell lung cancer.

Wu JY et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."