Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.T783I
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EGFR

NM_005228.5:p.T783I

Associated Papers

Deep mutational scanning reveals EGFR mutations conferring resistance to the 4th-generation EGFR tyrosine kinase inhibitor BLU-945.

Wang Y et al.

Npj Precision Oncology, 2025

Molecular landscape of ERBB2 alterations in 3000 advanced NSCLC patients.

Hong L et al.

Npj Precision Oncology, 2024

39354054 (PubMed )
Supplement: 41698_2024_720_MOESM1_ESM.pdf

EGFR Mutation Detection in Brazilian Patients With Non-Small-Cell Lung Cancer: Lessons From Real-World Data Scenario of Molecular Testing.

Montella T et al.

Jco Global Oncology, 2023

Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

Chevrier S et al.

International Journal of Molecular Medicine, 2022

35244186 (PubMed )
Supplement: Supplementary_Data2.xlsx › Feuil1

Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Ikeuchi H et al.

Oncogene, 2022

35304574 (PubMed )
Supplement: 41388_2022_2263_MOESM5_ESM.xlsx › Supplementary_Table_4

HER2 transmembrane domain mutation: comprehensive characteristics and real-world evidence of treatment response in Chinese lung adenocarcinoma.

Jia Z et al.

Translational Lung Cancer Research, 2021

Comprehensive Study of Germline Mutations and Double-Hit Events in Esophageal Squamous Cell Cancer.

Zeng B et al.

Frontiers in Oncology, 2021

33889545 (PubMed )
Supplement: Table_6.xlsx › Sheet1

ErBb Family Proteins in Cholangiocarcinoma and Clinical Implications.

Jin W

Journal of Clinical Medicine, 2020

Structural Stability and Flexibility Direct the Selection of Activating Mutations in Epidermal Growth Factor Receptor Kinase.

Paladino A et al.

Journal of Chemical Information and Modeling, 2015

26121158 (PubMed )
Supplement: ci5b00270_si_001.pdf

Efficacy analysis of tyrosine kinase inhibitors on rare non-small cell lung cancer patients harboring complex EGFR mutations.

Peng L et al.

Scientific Reports, 2014

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

The energy landscape analysis of cancer mutations in protein kinases.

Dixit A et al.

Plos One, 2011

21998754 (PubMed )
Supplement: pone.0026071.s009.doc

Epidemiology of doublet/multiplet mutations in lung cancers: evidence that a subset arises by chronocoordinate events.

Chen Z et al.

Plos One, 2008

A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening.

Jänne PA et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."