Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.L798F
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EGFR

NM_005228.5:p.L798F

Associated Papers

Beyond tobacco: genomic disparities in lung cancer between smokers and never-smokers.

Garrido J et al.

Bmc Cancer, 2024

Evolution of oncogenic signatures of mutation hotspots in tyrosine kinases supports the atavistic hypothesis of cancer.

Chen W et al.

Scientific Reports, 2018

29844492 (PubMed )
Supplement: 41598_2018_26653_MOESM2_ESM.xlsx › Dataset_S1

Structural Stability and Flexibility Direct the Selection of Activating Mutations in Epidermal Growth Factor Receptor Kinase.

Paladino A et al.

Journal of Chemical Information and Modeling, 2015

26121158 (PubMed )
Supplement: ci5b00270_si_001.pdf

A novel point mutation in exon 20 of EGFR showed sensitivity to erlotinib.

Xing K et al.

Medical Oncology (northwood, London, England), 2014

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

The energy landscape analysis of cancer mutations in protein kinases.

Dixit A et al.

Plos One, 2011

21998754 (PubMed )
Supplement: pone.0026071.s009.doc

Driver mutations and differential sensitivity to targeted therapies: a new approach to the treatment of lung adenocarcinoma.

Bronte G et al.

Cancer Treatment Reviews, 2010

[Mutations in the epidermal growth factor receptor: structure and biological function in human tumors].

Pedersen MW et al.

Ugeskrift for Laeger, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."