Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.R841K
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EGFR

NM_005228.5:p.R841K

Associated Papers

Beyond tobacco: genomic disparities in lung cancer between smokers and never-smokers.

Garrido J et al.

Bmc Cancer, 2024

EGFR Mutation Detection in Brazilian Patients With Non-Small-Cell Lung Cancer: Lessons From Real-World Data Scenario of Molecular Testing.

Montella T et al.

Jco Global Oncology, 2023

Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Ikeuchi H et al.

Oncogene, 2022

35304574 (PubMed )
Supplement: 41388_2022_2263_MOESM5_ESM.xlsx › Supplementary_Table_4

Identification of Recurrent TERT Promoter Mutations in Intrathyroid Thymic Carcinomas.

Tahara I et al.

Endocrine Pathology, 2020

Comutation and exclusion analysis in human tumors: A tool for cancer biology studies and for rational selection of multitargeted therapeutic approaches.

Ochoa S et al.

Human Mutation, 2019

Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase.

Truong TH et al.

Cell Chemical Biology, 2016

Structural Stability and Flexibility Direct the Selection of Activating Mutations in Epidermal Growth Factor Receptor Kinase.

Paladino A et al.

Journal of Chemical Information and Modeling, 2015

26121158 (PubMed )
Supplement: ci5b00270_si_001.pdf

ProKinO: a unified resource for mining the cancer kinome.

McSkimming DI et al.

Human Mutation, 2015

Screening for activating EGFR mutations in surgically resected nonsmall cell lung cancer.

Sriram KB et al.

The European Respiratory Journal, 2011

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer.

Peraldo-Neia C et al.

Bmc Cancer, 2011

The energy landscape analysis of cancer mutations in protein kinases.

Dixit A et al.

Plos One, 2011

21998754 (PubMed )
Supplement: pone.0026071.s009.doc

Epidermal growth factor receptor activation in prostate cancer by three novel missense mutations.

Cai CQ et al.

Oncogene, 2008

Novel mutations of epidermal growth factor receptor in localized prostate cancer.

Douglas DA et al.

Frontiers in Bioscience : a Journal and Virtual Library, 2006

Mutations of the epidermal growth factor receptor tyrosine kinase domain and associations with clinicopathological features in non-small cell lung cancer patients.

Murray S et al.

Lung Cancer (amsterdam, Netherlands), 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."