Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.T847A
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EGFR

NM_005228.5:p.T847A

Associated Papers

Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Ikeuchi H et al.

Oncogene, 2022

35304574 (PubMed )
Supplement: 41388_2022_2263_MOESM5_ESM.xlsx › Supplementary_Table_4

Evolution of oncogenic signatures of mutation hotspots in tyrosine kinases supports the atavistic hypothesis of cancer.

Chen W et al.

Scientific Reports, 2018

29844492 (PubMed )
Supplement: 41598_2018_26653_MOESM2_ESM.xlsx › Dataset_S1

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency.

Sun C et al.

Cancer Cell, 2018

Molecular spectrum of somatic EGFR and KRAS gene mutations in non small cell lung carcinoma: determination of frequency, distribution pattern and identification of novel variations in Indian patients.

Das BR et al.

Pathology Oncology Research : Por, 2015

EGFR mutational status in a large series of Caucasian European NSCLC patients: data from daily practice.

Gahr S et al.

British Journal of Cancer, 2013

DNA-Mutation Inventory to Refine and Enhance Cancer Treatment (DIRECT): a catalog of clinically relevant cancer mutations to enable genome-directed anticancer therapy.

Yeh P et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2013

Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer.

Yu J et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2009

Good response to gefitinib in lung adenocarcinoma of complex epidermal growth factor receptor (EGFR) mutations with the classical mutation pattern.

Wu SG et al.

The Oncologist, 2008

Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC.

Kalikaki A et al.

British Journal of Cancer, 2008

'Classical' but not 'other' mutations of EGFR kinase domain are associated with clinical outcome in gefitinib-treated patients with non-small cell lung cancer.

Pallis AG et al.

British Journal of Cancer, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."