Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.H850Y
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EGFR

NM_005228.5:p.H850Y

Associated Papers

Single-cell RNA profiling reveals an immunosuppressive microenvironment in EGFR double-mutant non-small cell lung cancer.

Yang J et al.

Translational Lung Cancer Research, 2025

41234595 (PubMed )
Supplement: tlcr-14-10-4235-supplementary.pdf

Concurrent EGFR L858R and K860I mutations: PCR-negative but NGS-positive alterations that respond to EGFR inhibitors in non-small cell lung cancer.

Shi H et al.

Journal of Thoracic Disease, 2025

Genomic comparison between cerebrospinal fluid and primary tumor revealed the genetic events associated with brain metastasis in lung adenocarcinoma.

Deng Z et al.

Cell Death & Disease, 2021

Exploring the spatiotemporal genetic heterogeneity in metastatic lung adenocarcinoma using a nuclei flow-sorting approach.

Lorber T et al.

The Journal of Pathology, 2019

Evolution of oncogenic signatures of mutation hotspots in tyrosine kinases supports the atavistic hypothesis of cancer.

Chen W et al.

Scientific Reports, 2018

29844492 (PubMed )
Supplement: 41598_2018_26653_MOESM2_ESM.xlsx › Dataset_S1

Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer.

Quan X et al.

Oncology Letters, 2018

High performance of targeted next generation sequencing on variance detection in clinical tumor specimens in comparison with current conventional methods.

Su D et al.

Journal of Experimental & Clinical Cancer Research : Cr, 2017

28882180 (PubMed )
Supplement: 13046_2017_591_MOESM8_ESM.xls › Table_S8__The_golden_standard_s

Patients with peritoneal mesothelioma lack epidermal growth factor receptor tyrosine kinase mutations that would make them sensitive to tyrosine kinase inhibitors.

Kalra N et al.

Oncology Reports, 2012

[Experience on epidermal growth factor receptor gene mutation analysis in non-small cell lung cancer].

Zhang J et al.

Zhonghua Bing Li Xue Za Zhi = Chinese Journal of Pathology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."