Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.F856L
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EGFR

NM_005228.5:p.F856L

Associated Papers

Mutational profiling using liquid biopsy to guide targeted therapy in patients with metastatic cancer.

Mazouji O et al.

Scientific Reports, 2025

40169620 (PubMed )
Supplement: 41598_2025_88094_MOESM2_ESM.xlsx › Feuil1

Automated Dashboards for the Identification of Pathogenic Circulating Tumor DNA Mutations in Longitudinal Blood Draws of Cancer Patients.

Udalov A et al.

Methods and Protocols, 2023

Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Wang JL et al.

Genes and Environment : the Official Journal of the Japanese Environmental Mutagen Society, 2022

35606799 (PubMed )
Supplement: 41021_2022_248_MOESM1_ESM.xlsx › Summary_table

Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Ikeuchi H et al.

Oncogene, 2022

35304574 (PubMed )
Supplement: 41388_2022_2263_MOESM5_ESM.xlsx › Supplementary_Table_4

An EGFR signature predicts cell line and patient sensitivity to multiple tyrosine kinase inhibitors.

Cheng C et al.

International Journal of Cancer, 2020

Integrative omics analyses broaden treatment targets in human cancer.

Sengupta S et al.

Genome Medicine, 2018

30053901 (PubMed )
Supplement: 13073_2018_564_MOESM2_ESM.xlsx › 10

Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer.

Quan X et al.

Oncology Letters, 2018

Computational and Experimental Characterization of Patient Derived Mutations Reveal an Unusual Mode of Regulatory Spine Assembly and Drug Sensitivity in EGFR Kinase.

Ruan Z et al.

Biochemistry, 2017

Discrimination of driver and passenger mutations in epidermal growth factor receptor in cancer.

Anoosha P et al.

Mutation Research, 2015

Structural Stability and Flexibility Direct the Selection of Activating Mutations in Epidermal Growth Factor Receptor Kinase.

Paladino A et al.

Journal of Chemical Information and Modeling, 2015

26121158 (PubMed )
Supplement: ci5b00270_si_001.pdf

A systematic profile of clinical inhibitors responsive to EGFR somatic amino acid mutations in lung cancer: implication for the molecular mechanism of drug resistance and sensitivity.

Ai X et al.

Amino Acids, 2014

Lack of mutations in protein tyrosine kinase domain coding exons 19 and 21 of the EGFR gene in oral squamous cell carcinomas.

Mehta DT et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2014

[Experience on epidermal growth factor receptor gene mutation analysis in non-small cell lung cancer].

Zhang J et al.

Zhonghua Bing Li Xue Za Zhi = Chinese Journal of Pathology, 2011

Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer.

Peraldo-Neia C et al.

Bmc Cancer, 2011

The energy landscape analysis of cancer mutations in protein kinases.

Dixit A et al.

Plos One, 2011

21998754 (PubMed )
Supplement: pone.0026071.s009.doc

Good response to gefitinib in lung adenocarcinoma of complex epidermal growth factor receptor (EGFR) mutations with the classical mutation pattern.

Wu SG et al.

The Oncologist, 2008

Novel heteroduplex method using small cytology specimens with a remarkably high success rate for analysing EGFR gene mutations with a significant correlation to gefitinib efficacy in non-small-cell lung cancer.

Oshita F et al.

British Journal of Cancer, 2006

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