Varaico: Literature-Extracted Genetic Variants

Gene:EGFR
Variant:p.E865A
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EGFR

NM_005228.5:p.E865A

Associated Papers

A covalent fragment-based strategy targeting a novel cysteine to inhibit activity of mutant EGFR kinase.

Kuki N et al.

Rsc Medicinal Chemistry, 2023

Structural Basis of AZD9291 Selectivity for EGFR T790M.

Yan XE et al.

Journal of Medicinal Chemistry, 2020

Discovery of selective and noncovalent diaminopyrimidine-based inhibitors of epidermal growth factor receptor containing the T790M resistance mutation.

Hanan EJ et al.

Journal of Medicinal Chemistry, 2014

25383627 (PubMed )
Supplement: jm501578n_si_001.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."