Varaico: Literature-Extracted Genetic Variants

Gene:EGR2
Variant:p.H384N
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EGR2

NM_000399.5:p.H384N

Associated Papers

All-CLL: A Capture-based Next-generation Sequencing Panel for the Molecular Characterization of Chronic Lymphocytic Leukemia.

López-Oreja I et al.

Hemasphere, 2023

37746159 (PubMed )
Supplement: hs9-7-e962-s002.xlsx › Table_S7

Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.

Mansouri L et al.

Leukemia, 2023

Characterization of clonal immunoglobulin heavy V-D-J gene rearrangements in Chinese patients with chronic lymphocytic leukemia: Clinical features and molecular profiles.

Deng X et al.

Frontiers in Oncology, 2023

36874132 (PubMed )
Supplement: Table_1.xlsx › Sheet1

Clonally unrelated Richter syndrome are truly de novo diffuse large B-cell lymphomas with a mutational profile reminiscent of clonally related Richter syndrome.

Favini C et al.

British Journal of Haematology, 2022

35829664 (PubMed )
Supplement: BJH-198-1016-s001.xlsx › Table_S4

Circulating tumor DNA for comprehensive noninvasive monitoring of lymphoma treated with ibrutinib plus nivolumab.

Bruscaggin A et al.

Blood Advances, 2021

34500472 (PubMed )
Supplement: advancesADV2021004528-suppl2.xlsx › Table_S7

Multiregional sequencing and circulating tumour DNA analysis provide complementary approaches for comprehensive disease profiling of small lymphocytic lymphoma.

Moia R et al.

British Journal of Haematology, 2021

34291829 (PubMed )
Supplement: BJH-195-108-s003.xlsx › Table_S2

Genomic mutation profile in progressive chronic lymphocytic leukemia patients prior to first-line chemoimmunotherapy with FCR and rituximab maintenance (REM).

González-Rincón J et al.

Plos One, 2021

34506616 (PubMed )
Supplement: pone.0257353.s001.xlsx › Table_S3._SNVs

Genetic dynamics in untreated CLL patients with either stable or progressive disease: a longitudinal study.

Ramassone A et al.

Journal of Hematology & Oncology, 2019

31744508 (PubMed )
Supplement: 13045_2019_802_MOESM4_ESM.pdf

Novel Richter Syndrome Xenograft Models to Study Genetic Architecture, Biology, and Therapy Responses.

Vaisitti T et al.

Cancer Research, 2018

Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia.

Nadeu F et al.

Leukemia, 2018

28924241 (PubMed )
Supplement: leu2017291x1.pdf

Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia.

Herling CD et al.

Nature Communications, 2018

29463802 (PubMed )
Supplement: 41467_2018_3170_MOESM4_ESM.xlsx › Somatic_Mutations

The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy.

Landau DA et al.

Nature Communications, 2017

29259203 (PubMed )
Supplement: 41467_2017_2329_MOESM4_ESM.xlsx › Supplementary_Data_2

EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia.

Young E et al.

Leukemia, 2017

Genomic characterization of high-count MBL cases indicates that early detection of driver mutations and subclonal expansion are predictors of adverse clinical outcome.

Barrio S et al.

Leukemia, 2017

27469216 (PubMed )
Supplement: NIHMS793139-supplement-3.xlsx › S3

Mutations driving CLL and their evolution in progression and relapse.

Landau DA et al.

Nature, 2015

26466571 (PubMed )
Supplement: NIHMS715090-supplement-Supplementary_Table_10.xlsx › CCF_DP_clustering

Monoclonal B-cell lymphocytosis is characterized by mutations in CLL putative driver genes and clonal heterogeneity many years before disease progression.

Ojha J et al.

Leukemia, 2014

Acquired initiating mutations in early hematopoietic cells of CLL patients.

Damm F et al.

Cancer Discovery, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."