Varaico: Literature-Extracted Genetic Variants

Gene:EIF2AK1
Variant:p.K196R
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EIF2AK1

NM_014413.4:p.K196R

Associated Papers

Autophosphorylation of heme-regulated eukaryotic initiation factor 2α kinase and the role of the modification in catalysis.

Igarashi J et al.

The Febs Journal, 2011

Characterization of heme-regulated eIF2alpha kinase: roles of the N-terminal domain in the oligomeric state, heme binding, catalysis, and inhibition.

Miksanova M et al.

Biochemistry, 2006

Autophosphorylation of threonine 485 in the activation loop is essential for attaining eIF2alpha kinase activity of HRI.

Rafie-Kolpin M et al.

Biochemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."