Varaico: Literature-Extracted Genetic Variants

Gene:EIF2AK2
Variant:p.T446A
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EIF2AK2

NM_001135651.3:p.T446A

Associated Papers

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S5

Viral Evolved Inhibition Mechanism of the RNA Dependent Protein Kinase PKR's Kinase Domain, a Structural Perspective.

Krishna KH et al.

Plos One, 2016

Molecular framework for the activation of RNA-dependent protein kinase.

McKenna SA et al.

The Journal of Biological Chemistry, 2007

Mechanistic link between PKR dimerization, autophosphorylation, and eIF2alpha substrate recognition.

Dey M et al.

Cell, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."