Associated Papers
CD147 promotes NSCLC metastasis by inducing secretory autophagy-dependent exosome secretion via TRIM56-mediated ubiquitination and degradation of GCN2.
Yang J et al.
Cell Death and Differentiation, 2025
Functional validation of EIF2AK4 (GCN2) missense variants associated with pulmonary arterial hypertension.
Emanuelli G et al.
Human Molecular Genetics, 2024
The GCN2/eIF2αK stress kinase regulates PP1 to ensure mitotic fidelity.
Stonyte V et al.
Embo Reports, 2023
CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells.
Surka C et al.
Blood, 2021
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