Varaico: Literature-Extracted Genetic Variants

Gene:EIF4EBP1
Variant:p.S65A
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EIF4EBP1

NM_004095.4:p.S65A

Associated Papers

PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1 dephosphorylation by PP1-Neurabin.

Fedoryshchak RO et al.

Elife, 2025

Chemoproteomic Profiling Uncovers CDK4-Mediated Phosphorylation of the Translational Suppressor 4E-BP1.

Mitchell DC et al.

Cell Chemical Biology, 2019

CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stability.

Choi SH et al.

Genes & Development, 2019

Accumulation of dephosphorylated 4EBP after mTOR inhibition with rapamycin is sufficient to disrupt paracrine transformation by the KSHV vGPCR oncogene.

Martin D et al.

Oncogene, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."