Varaico: Literature-Extracted Genetic Variants

Gene:EIF5A
Variant:p.K50R
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EIF5A

NM_001970.5:p.K50R

Associated Papers

Hypusinated and unhypusinated isoforms of the translation factor eIF5A exert distinct effects in models of pancreas development and function.

Anderson CM et al.

The Journal of Biological Chemistry, 2025

Hypusination of Eif5a regulates cytoplasmic TDP-43 aggregation and accumulation in a stress-induced cellular model.

Smeltzer S et al.

Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2021

Mutational analyses of human eIF5A-1--identification of amino acid residues critical for eIF5A activity and hypusine modification.

Cano VS et al.

The Febs Journal, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."