Associated Papers
Ribonuclease RNase Z is an evolutionarily conserved deAMPylase.
Mukherjee M et al.
Proceedings of the National Academy of Sciences of the United States of America, 2025
Structural insights into human ELAC2 as a tRNA 3' processing enzyme.
Xue C et al.
Nucleic Acids Research, 2024
Human Cytochrome P450 Cancer-Related Metabolic Activities and Gene Polymorphisms: A Review.
Mokhosoev IM et al.
Cells, 2024
Evaluation of HNF1B, KLK3, ELAC2, TMPRSS2-ERG, and CTNNB1 polymorphisms associated with prostate cancer in samples of patients from HUPE-UERJ.
Menezes RDS et al.
The Prostate, 2024
Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer.
Stentenbach M et al.
Embo Molecular Medicine, 2023
A Case Study on PPM1D and 9 Other Shared Germline Alterations in a Family.
Biswas S et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2023
Carriage of Ser217Leu and Ala541Thr Variants of ELAC2 Gene and Risk Factors in Patients with Prostate Cancer in Burkina Faso.
Traoré ADD et al.
Prostate Cancer, 2022
Identification of New Tumor-Related Gene Mutations in Chinese Gastrointestinal Stromal Tumors.
Feng Y et al.
Frontiers in Cell and Developmental Biology, 2021
A Study of Ser217Leu and Ala541Thr Polymorphism in the Men Afflicted with Prostate Cancer and in the Men being Suspicious of Prostate Cancer.
Zahiri Z et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2020
The Impact of Whole Genome Data on Therapeutic Decision-Making in Metastatic Prostate Cancer: A Retrospective Analysis.
Crumbaker M et al.
Cancers, 2020
Lifetime risk of autosomal recessive mitochondrial disorders calculated from genetic databases.
Tan J et al.
Ebiomedicine, 2020
The functional landscape of the human phosphoproteome.
Ochoa D et al.
Nature Biotechnology, 2020
Systematic analysis of the intersection of disease mutations with protein modifications.
Simpson CM et al.
Bmc Medical Genomics, 2019
Comprehensive analysis of age-related somatic mutation profiles in Chinese young lung adenocarcinoma patients.
Yang B et al.
Cancer Medicine, 2019
Prevalence of the Ser217Leu Variant of the ELAC2 Gene and Its Association with Prostate Cancer in Population of the Littoral Region of Cameroon.
Djomkam ALZ et al.
Prostate Cancer, 2019
Assessment of coding region variants in Kuwaiti population: implications for medical genetics and population genomics.
John SE et al.
Scientific Reports, 2018
Arylsulphatase A Pseudodeficiency (ARSA-PD), hypertension and chronic renal disease in Aboriginal Australians.
Tang D et al.
Scientific Reports, 2018
The molecular biology of prostate cancer: current understanding and clinical implications.
Gandhi J et al.
Prostate Cancer and Prostatic Diseases, 2018
The crystal structure of Trz1, the long form RNase Z from yeast.
Ma M et al.
Nucleic Acids Research, 2017
A knowledge-based framework for the discovery of cancer-predisposing variants using large-scale sequencing breast cancer data.
Melloni GEM et al.
Breast Cancer Research : Bcr, 2017
Prognostic role of genetic biomarkers in clinical progression of prostate cancer.
Alvarez-Cubero MJ et al.
Experimental & Molecular Medicine, 2015
Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach.
Karageorgos I et al.
Human Genomics, 2015
Whole genome sequencing of an ethnic Pathan (Pakhtun) from the north-west of Pakistan.
Ilyas M et al.
Bmc Genomics, 2015
Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.
Holehouse AS et al.
Plos One, 2015
TBX1 mutation identified by exome sequencing in a Japanese family with 22q11.2 deletion syndrome-like craniofacial features and hypocalcemia.
Ogata T et al.
Plos One, 2014
Genetic analysis of the principal genes related to prostate cancer: a review.
Alvarez-Cubero MJ et al.
Urologic Oncology, 2013
ELAC2 mutations cause a mitochondrial RNA processing defect associated with hypertrophic cardiomyopathy.
Haack TB et al.
American Journal of Human Genetics, 2013
Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.
Haiman CA et al.
Plos Genetics, 2013
Sequencing and analysis of a South Asian-Indian personal genome.
Gupta R et al.
Bmc Genomics, 2012
Polymorphisms in the HPC/ELAC-2 and alpha 1-antitrypsin genes that correlate with human diseases in a North Indian population.
Sobti RC et al.
Molecular Biology Reports, 2011
Polymorphisms of HPC2/ELAC2 and SRD5A2 (5α-Reductase Type II) Genes in Prostate Cancer.
Izmirli M et al.
Balkan Journal of Medical Genetics : Bjmg, 2011
Associations of polymorphisms in HPC2/ELAC2 and SRD5A2 genes with benign prostate hyperplasia in Turkish men.
Izmirli M et al.
Asian Pacific Journal of Cancer Prevention : Apjcp, 2011
ELAC2 polymorphisms and prostate cancer risk: a meta-analysis based on 18 case-control studies.
Xu B et al.
Prostate Cancer and Prostatic Diseases, 2010
Single and multivariate associations of MSR1, ELAC2, and RNASEL with prostate cancer in an ethnic diverse cohort of men.
Beuten J et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2010
Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes.
Breyer JP et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2009
Development of a fingerprinting panel using medically relevant polymorphisms.
Cross DS et al.
Bmc Medical Genomics, 2009
Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.
Ryu GM et al.
Nucleic Acids Research, 2009
Association of HPC2/ELAC2 and RNASEL non-synonymous variants with prostate cancer risk in African American familial and sporadic cases.
Robbins CM et al.
The Prostate, 2008
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.
Ley TJ et al.
Nature, 2008
Sequence variants of elaC homolog 2 (Escherichia coli) (ELAC2) gene and susceptibility to prostate cancer in the Health Professionals Follow-Up Study.
Chen YC et al.
Carcinogenesis, 2008
SNPs associated with prostate cancer risk and prognosis.
Naylor SL
Frontiers in Bioscience : a Journal and Virtual Library, 2007
Systematic replication study of reported genetic associations in prostate cancer: Strong support for genetic variation in the androgen pathway.
Lindström S et al.
The Prostate, 2006
Association of hereditary prostate cancer gene polymorphic variants with sporadic aggressive prostate carcinoma.
Noonan-Wheeler FC et al.
The Prostate, 2006
The missense mutations in the candidate prostate cancer gene ELAC2 do not alter enzymatic properties of its product.
Minagawa A et al.
Cancer Letters, 2005
Characterization of TRZ1, a yeast homolog of the human candidate prostate cancer susceptibility gene ELAC2 encoding tRNase Z.
Chen Y et al.
Bmc Molecular Biology, 2005
Characterization of linkage disequilibrium structure, mutation history, and tagging SNPs, and their use in association analyses: ELAC2 and familial early-onset prostate cancer.
Camp NJ et al.
Genetic Epidemiology, 2005