Varaico: Literature-Extracted Genetic Variants

Gene:ELAVL1
Variant:p.S221A
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ELAVL1

NM_001419.3:p.S221A

Associated Papers

In Silico Structural Modeling of the HuR-mRNA Complex: Insights into Structural and Functional Regulation.

Pietrafesa D et al.

Journal of Chemical Information and Modeling, 2025

Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR.

Battaglia-Hsu SF et al.

Nucleic Acids Research, 2018

The mRNA-stabilizing factor HuR protein is targeted by β-TrCP protein for degradation in response to glycolysis inhibition.

Chu PC et al.

The Journal of Biological Chemistry, 2012

Modification at HuR(S242) alters HuR localization and proliferative influence.

Kim HH et al.

Cell Cycle (georgetown, Tex.), 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."