Varaico: Literature-Extracted Genetic Variants

Gene:EML4
Variant:p.V285D
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EML4

NM_019063.5:p.V285D

Associated Papers

Utility of the Ba/F3 cell system for exploring on-target mechanisms of resistance to targeted therapies for lung cancer.

Koga T et al.

Cancer Science, 2022

34997674 (PubMed )
Supplement: CAS-113-815-s001.pdf

Analysis of the frequency of oncogenic driver mutations and correlation with clinicopathological characteristics in patients with lung adenocarcinoma from Northeastern Switzerland.

Grosse A et al.

Diagnostic Pathology, 2019

Overcoming resistance to first/second generation epidermal growth factor receptor tyrosine kinase inhibitors and ALK inhibitors in oncogene-addicted advanced non-small cell lung cancer.

Romanidou O et al.

Therapeutic Advances in Medical Oncology, 2016

Mechanisms of resistance to EGFR tyrosine kinase inhibitors.

Huang L et al.

Acta Pharmaceutica Sinica. B, 2015

Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations-a review.

Stewart EL et al.

Translational Lung Cancer Research, 2015

Genetic and epigenetic changes in lung carcinoma and their clinical implications.

Wen J et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2011

EGFR mutations and the terminal respiratory unit.

Yatabe Y

Cancer Metastasis Reviews, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."