Varaico: Literature-Extracted Genetic Variants

Gene:EML4
Variant:p.G719A
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EML4

NM_019063.5:p.G719A

Associated Papers

A prospective, multicenter, comprehensive genomic profile signature study in patients with EGFR-mutant advanced non-small cell lung cancer at the first-line treatment failure of osimertinib.

Shi Y et al.

Signal Transduction and Targeted Therapy, 2025

41326340 (PubMed )
Supplement: 41392_2025_2481_MOESM1_ESM.docx

Genetic alterations affect immune contexture of non-small cell lung cancer: Ukrainian study.

Kozakov D et al.

Frontiers in Medicine, 2025

Durable response to afatinib rechallenge in a long-term survivor of non-small cell lung cancer harboring EGFR L858R and L747V mutations.

Kanbe M et al.

Thoracic Cancer, 2022

36193787 (PubMed )
Supplement: TCA-13-3225-s001.docx

Comprehensive genomic profiling of Finnish lung adenocarcinoma cohort reveals high clinical actionability and SMARCA4 altered tumors with variable histology and poor prognosis.

Talvitie EM et al.

Neoplasia (new York, N.y.), 2022

Comprehensive analyses of genomic features and mutational signatures in adenosquamous carcinoma of the lung.

Wang H et al.

Frontiers in Oncology, 2022

Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung cancer: Analysis of over 8000 cases.

Mack PC et al.

Cancer, 2020

Identifying a wide range of actionable variants using capture-based ultra-deep targeted sequencing in treatment-naive patients with primary lung adenocarcinoma.

Chen L et al.

International Journal of Clinical and Experimental Pathology, 2020

Comparison of next-generation sequencing and immunohistochemistry analysis for targeted therapy-related genomic status in lung cancer patients.

Nong L et al.

Journal of Thoracic Disease, 2019

Genomic Signature of Driver Genes Identified by Target Next-Generation Sequencing in Chinese Non-Small Cell Lung Cancer.

Wen S et al.

The Oncologist, 2019

Targeted sequencing reveals distinct pathogenic variants in Chinese patients with lung adenocarcinoma brain metastases.

Ma Y et al.

Oncology Letters, 2018

Mutation testing for directing upfront targeted therapy and post-progression combination therapy strategies in lung adenocarcinoma.

Salgia R

Expert Review of Molecular Diagnostics, 2016

Somatic Mutation Spectrum of Non-Small-Cell Lung Cancer in African Americans: A Pooled Analysis.

Araujo LH et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2015

Anaplastic lymphoma kinase translocation is correlated with anaplastic lymphoma kinase expression and mutually exclusive with epidermal growth factor receptor mutation in Taiwanese non-small cell lung cancer.

Hsu SC et al.

Pathology International, 2015

Patterns of DNA mutations and ALK rearrangement in resected node negative lung adenocarcinoma.

Yip PY et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2013

EGFR mutation testing in patients with advanced non-small cell lung cancer: a comprehensive evaluation of real-world practice in an East Asian tertiary hospital.

Choi YL et al.

Plos One, 2013

[Molecular profiling of non-small cell lung cancer].

Gibault L et al.

Revue De Pneumologie Clinique, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."