Varaico: Literature-Extracted Genetic Variants

Gene:EPHA2
Variant:p.E825K
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EPHA2

NM_004431.5:p.E825K

Associated Papers

Frequent EPHA2 receptor mutations in cholangiocarcinoma disrupt receptor forward signaling supporting a tumor suppressor role.

Koutouan E et al.

Biochimica Et Biophysica Acta. Molecular Cell Research, 2026

Unravelling the role of PLK1 in tumorigenesis by revealing the mutational landscape of colorectal and lung cancer with PLK1 mutations.

Wang S et al.

Journal of Cellular and Molecular Medicine, 2024

38887977 (PubMed )
Supplement: JCMM-28-e18497-s002.xlsx › Sheet1

Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker.

Lechtenberg BC et al.

Nature Communications, 2021

Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns.

Mateo L et al.

Genome Medicine, 2020

32907621 (PubMed )
Supplement: 13073_2020_774_MOESM1_ESM.zip › SupplementaryTables › TableS2.xlsx › Driver_Mutations

Functional significance of U2AF1 S34F mutations in lung adenocarcinomas.

Esfahani MS et al.

Nature Communications, 2019

31836708 (PubMed )
Supplement: 41467_2019_13392_MOESM3_ESM.xlsx › Supplementary_Data_1_a_

Germ-line and somatic EPHA2 coding variants in lens aging and cataract.

Bennett TM et al.

Plos One, 2017

The Polymorphisms with Cataract Susceptibility Impair the EPHA2 Receptor Stability and Its Cytoprotective Function.

Yang J et al.

Journal of Ophthalmology, 2015

Screening and structural evaluation of deleterious Non-Synonymous SNPs of ePHA2 gene involved in susceptibility to cataract formation.

Masoodi TA et al.

Bioinformation, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."