Associated Papers
Understanding the influence of AMG 510 on the structure of KRASG12C empowered by molecular dynamics simulation.
Li Y et al.
Computational and Structural Biotechnology Journal, 2022
NMR in integrated biophysical drug discovery for RAS: past, present, and future.
Marshall CB et al.
Journal of Biomolecular Nmr, 2020
What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf.
Filchtinski D et al.
Journal of Molecular Biology, 2010
Improved binding of raf to Ras.GDP is correlated with biological activity.
Kiel C et al.
The Journal of Biological Chemistry, 2009
RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao.
Traver S et al.
The Biochemical Journal, 2000
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