Varaico: Literature-Extracted Genetic Variants

Gene:EPHB3
Variant:p.K665R
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EPHB3

NM_004443.4:p.K665R

Associated Papers

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S5

EphB3 suppresses non-small-cell lung cancer metastasis via a PP2A/RACK1/Akt signalling complex.

Li G et al.

Nature Communications, 2012

Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases.

Miao H et al.

The Journal of Biological Chemistry, 2005

Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk.

Halford MM et al.

Nature Genetics, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."