Varaico: Literature-Extracted Genetic Variants

Gene:EPHX2
Variant:p.R103C
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EPHX2

NM_001979.6:p.R103C

Associated Papers

CYP metabolic pathway related gene polymorphism increases the risk of embolic and atherothrombotic stroke and vulnerable carotid plaque in southeast China.

Shao M et al.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association, 2023

The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease.

Gautheron J et al.

International Journal of Molecular Sciences, 2020

The Co-existence of ADHD With Autism in Saudi Children: An Analysis Using Next-Generation DNA Sequencing.

Bogari NM et al.

Frontiers in Genetics, 2020

The metabolism of lysophosphatidic acids by allelic variants of human soluble epoxide hydrolase.

Purba ER et al.

Drug Metabolism and Pharmacokinetics, 2015

De novo mutations in moderate or severe intellectual disability.

Hamdan FF et al.

Plos Genetics, 2014

25356899 (PubMed )
Supplement: pgen.1004772.s004.xlsx › 820.316

Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation.

Morisseau C et al.

Journal of Lipid Research, 2014

Genetically reduced soluble epoxide hydrolase activity and risk of stroke and other cardiovascular disease.

Lee J et al.

Stroke, 2010

Protein quaternary structure and expression levels contribute to peroxisomal-targeting-sequence-1-mediated peroxisomal import of human soluble epoxide hydrolase.

Luo B et al.

Journal of Molecular Biology, 2008

Genetic variations in soluble epoxide hydrolase and graft function in kidney transplantation.

Lee SH et al.

Transplantation Proceedings, 2008

Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury.

Koerner IP et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2007

Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study.

Lee CR et al.

Human Molecular Genetics, 2006

Effects of human soluble epoxide hydrolase polymorphisms on isoprenoid phosphate hydrolysis.

Enayetallah AE et al.

Biochemical and Biophysical Research Communications, 2006

The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke.

Fornage M et al.

Human Molecular Genetics, 2005

Polymorphisms in human soluble epoxide hydrolase: effects on enzyme activity, enzyme stability, and quaternary structure.

Srivastava PK et al.

Archives of Biochemistry and Biophysics, 2004

Polymorphisms in human soluble epoxide hydrolase.

Przybyla-Zawislak BD et al.

Molecular Pharmacology, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."