Associated Papers
Whole-Genome Sequencing Reveals a Novel GATA2 Mutation in Lower-Grade Glioma: Bioinformatics Analysis of Functional and Therapeutic Implications.
Handoko et al.
Cancers, 2025
Association between the sEH rs751141 polymorphism and the risk of ischemic stroke and hypertension: A systematic review and meta-analysis.
Fan Z et al.
Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association, 2025
Genetic analysis and management of a familial hypercholesterolemia pedigree with polygenic variants: Case report.
Han Y et al.
Medicine, 2023
CYP metabolic pathway related gene polymorphism increases the risk of embolic and atherothrombotic stroke and vulnerable carotid plaque in southeast China.
Shao M et al.
Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association, 2023
Genetic variants in epoxyeicosatrienoic acid processing and degradation pathways are associated with gestational diabetes mellitus.
Lai S et al.
Nutrition Journal, 2023
Decoding the genetic relationship between Alzheimer's disease and type 2 diabetes: potential risk variants and future direction for North Africa.
Boukhalfa W et al.
Frontiers in Aging Neuroscience, 2023
Expanding the genetic spectrum for Chinese familial hypercholesterolemia population with six genetic mutations identified using a next-generation sequencing-based laboratory-developed screening test.
Jingxin S et al.
Molecular Genetics & Genomic Medicine, 2022
A hypothesis-driven study to comprehensively investigate the association between genetic polymorphisms in EPHX2 gene and cardiovascular diseases: Findings from the UK Biobank.
Zhu X et al.
Gene, 2022
Genetics Variants in the Epoxygenase Pathway of Arachidonic Metabolism Are Associated with Eicosanoids Levels and the Risk of Diabetic Nephropathy.
Mota-Zamorano S et al.
Journal of Clinical Medicine, 2021
No impact of soluble epoxide hydrolase rs4149243, rs2234914 and rs751142 genetic variants on the development of type II diabetes and its hypertensive complication among Jordanian patients.
Khamees M et al.
International Journal of Clinical Practice, 2021
Discovering Genotype Variants in an Infant with VACTERL through Clinical Exome Sequencing: A Support for Personalized Risk Assessment and Disease Prevention.
Pelizzo G et al.
Pediatric Reports, 2021
The Multifaceted Role of Epoxide Hydrolases in Human Health and Disease.
Gautheron J et al.
International Journal of Molecular Sciences, 2020
Association of Epoxide Hydrolase 2 Gene Arg287Gln with the Risk for Primary Hypertension in Chinese.
Ma L et al.
International Journal of Hypertension, 2020
The Human Genetic Variants CYP2J2 rs2280275 and EPHX2 rs751141 and Risk of Diabetic Nephropathy in Egyptian Type 2 Diabetic Patients.
Habieb MS et al.
The Application of Clinical Genetics, 2020
The Co-existence of ADHD With Autism in Saudi Children: An Analysis Using Next-Generation DNA Sequencing.
Bogari NM et al.
Frontiers in Genetics, 2020
Missense Genetic Polymorphisms of Microsomal (EPHX1) and Soluble Epoxide Hydrolase (EPHX2) and Their Relation to the Risk of Large Artery Atherosclerotic Ischemic Stroke in a Turkish Population.
Can Demirdöğen B et al.
Neuropsychiatric Disease and Treatment, 2020
Genetic associations between genes in the renin-angiotensin-aldosterone system and renal disease: a systematic review and meta-analysis.
Smyth LJ et al.
Bmj Open, 2019
Interaction of MTHFR C677T polymorphism with smoking in susceptibility to diabetic nephropathy in Chinese men with type 2 diabetes.
Ma L et al.
Journal of Human Genetics, 2019
Polymorphisms in vasoactive eicosanoid genes of kidney donors affect biopsy scores and clinical outcomes in renal transplantation.
Mota-Zamorano S et al.
Plos One, 2019
Soluble Epoxide Hydrolase and Brain Cholesterol Metabolism.
Domingues MF et al.
Frontiers in Molecular Neuroscience, 2019
Association between the EPHX2 p.Lys55Arg polymorphism and prognosis following an acute coronary syndrome.
Oni-Orisan A et al.
Prostaglandins & Other Lipid Mediators, 2018
Role of sEH R287Q in LDLR expression, LDL binding to LDLR and LDL internalization in BEL-7402 cells.
Tang L et al.
Gene, 2018
Association of EPHX2 R287Q Polymorphism with Diabetic Nephropathy in Chinese Type 2 Diabetic Patients.
Ma L et al.
Journal of Diabetes Research, 2018
Association between the soluble epoxide hydrolase gene and preeclampsia.
Sari I et al.
Hypertension in Pregnancy, 2017
Cytochrome P450 epoxygenase-derived epoxyeicosatrienoic acids contribute to insulin sensitivity in mice and in humans.
Gangadhariah MH et al.
Diabetologia, 2017
Association of CYP2J2 gene polymorphisms with ischemic stroke and stroke subtypes in Chinese population.
Wang SY et al.
Medicine, 2017
Synergistic Effect of the MTHFR C677T and EPHX2 G860A Polymorphism on the Increased Risk of Ischemic Stroke in Chinese Type 2 Diabetic Patients.
Ma L et al.
Journal of Diabetes Research, 2017
Association of gain-of-function EPHX2 polymorphism Lys55Arg with acute kidney injury following cardiac surgery.
Shuey MM et al.
Plos One, 2017
Ischemic Stroke and Six Genetic Variants in CRP, EPHX2, FGA, and NOTCH3 Genes: A Meta-Analysis.
González-Giraldo Y et al.
Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association, 2016
Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa.
Shih PB et al.
Molecular Psychiatry, 2016
Distribution of single-nucleotide variants on protein-protein interaction sites and its relationship with minor allele frequency.
Nishi H et al.
Protein Science : a Publication of the Protein Society, 2016
Disrupting Dimerization Translocates Soluble Epoxide Hydrolase to Peroxisomes.
Nelson JW et al.
Plos One, 2016
Intakes of omega-3 polyunsaturated fatty acids and blood pressure change over time: Possible interaction with genes involved in 20-HETE and EETs metabolism.
Tagetti A et al.
Prostaglandins & Other Lipid Mediators, 2015
Relationship between EPHX2 gene polymorphisms and essential hypertension in Uygur, Kazakh, and Han.
Zhu XL et al.
Genetics and Molecular Research : Gmr, 2015
Genetic polymorphisms of ALOX5AP and CYP3A5 increase susceptibility to ischemic stroke and are associated with atherothrombotic events in stroke patients.
Yi X et al.
Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association, 2015
Genetic markers in the EET metabolic pathway are associated with outcomes in patients with aneurysmal subarachnoid hemorrhage.
Donnelly MK et al.
Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism, 2015
The metabolism of lysophosphatidic acids by allelic variants of human soluble epoxide hydrolase.
Purba ER et al.
Drug Metabolism and Pharmacokinetics, 2015
A 3'-UTR Polymorphism in Soluble Epoxide Hydrolase Gene Is Associated with Acute Rejection in Renal Transplant Recipients.
Gervasini G et al.
Plos One, 2015
Arg287Gln variant of EPHX2 and epoxyeicosatrienoic acids are associated with insulin sensitivity in humans.
Ramirez CE et al.
Prostaglandins & Other Lipid Mediators, 2014
Role of soluble epoxide hydrolase in age-related vascular cognitive decline.
Nelson JW et al.
Prostaglandins & Other Lipid Mediators, 2014
Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation.
Morisseau C et al.
Journal of Lipid Research, 2014
Interaction between ALOX5AP and CYP3A5 gene variants significantly increases the risk for cerebral infarctions in Chinese.
Chi LF et al.
Neuroreport, 2014
Human genetics of diabetic vascular complications.
Tang ZH et al.
Journal of Genetics, 2013
Variations in the human soluble epoxide hydrolase gene and recurrence of atrial fibrillation after catheter ablation.
Wutzler A et al.
International Journal of Cardiology, 2013
Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease.
Cooper DN et al.
Human Genetics, 2013
Soluble epoxide hydrolase dimerization is required for hydrolase activity.
Nelson JW et al.
The Journal of Biological Chemistry, 2013
Genetic variants in epoxide hydrolases modify the risk of oligozoospermia and asthenospermia in Han-Chinese population.
Qin Y et al.
Gene, 2012