Associated Papers
The Genetic Background of Ankylosing Spondylitis Reveals a Distinct Overlap with Autoimmune Diseases: A Systematic Review.
Zormpa T et al.
Journal of Clinical Medicine, 2025
Defining a genetic background for bamboo spine and axial spondyloarthritis.
Özkaya ŞÇ et al.
Joint Bone Spine, 2025
Endogamy and high prevalence of deleterious mutations in India: evidence from strong founder events.
Machha P et al.
Journal of Genetics and Genomics = Yi Chuan Xue Bao, 2025
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.
Dand N et al.
Nature Communications, 2025
Proteogenomic Profiling of Treatment-Naïve Metastatic Malignant Melanoma.
Kuras M et al.
Cancers, 2025
ERAP1 Gene Variants and Haplotypes Associated With Psoriasis Vulgaris of Han Chinese in Inner Mongolia.
Li X et al.
Molecular Genetics & Genomic Medicine, 2024
The Role of Aminopeptidase ERAP1 in Human Pathology-A Review.
Țiburcă L et al.
Current Issues in Molecular Biology, 2024
Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population.
Kril I et al.
Frontiers in Immunology, 2024
Shedding Light on the Role of ERAP1 in Axial Spondyloarthritis.
Saad MA et al.
Cureus, 2023
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.
Dand N et al.
Medrxiv : the Preprint Server for Health Sciences, 2023
Indicators of HSV1 Infection, ECM-Receptor Interaction, and Chromatin Modulation in a Nuclear Family with Schizophrenia.
Huang YC et al.
Journal of Personalized Medicine, 2023
Single-cell genome-wide association reveals that a nonsynonymous variant in ERAP1 confers increased susceptibility to influenza virus.
Schott BH et al.
Cell Genomics, 2022
ERAP/HLA-C and KIR Genetic Profile in Couples with Recurrent Implantation Failure.
Piekarska K et al.
International Journal of Molecular Sciences, 2022
H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma.
Immisch L et al.
Journal for Immunotherapy of Cancer, 2022
Functional ERAP1 Variants Distinctively Associate with Ankylosing Spondylitis Susceptibility under the Influence of HLA-B27 in Taiwanese.
Wang CM et al.
Cells, 2022
HLA-B27 may modulate the interaction between ERAP1 polymorphisms and smoking in ankylosing spondylitis patients.
Fernández-Torres J et al.
Molecular Biology Reports, 2022
The emerging multifunctional roles of ERAP1, ERAP2 and IRAP between antigen processing and renin-angiotensin system modulation.
Mattorre B et al.
Frontiers in Immunology, 2022
ERAP1 binds peptide C-termini of different sequences and/or lengths by a common recognition mechanism.
Sui L et al.
Immunobiology, 2021
A First Step for the Molecular Characterization of Neurological Involvement of Behçet Syndrome: an Italian Pivotal Study.
Padula MC et al.
Journal of Molecular Neuroscience : Mn, 2021
Aberrant antigen processing and presentation: Key pathogenic factors leading to immune activation in Ankylosing spondylitis.
Nakamura A et al.
Seminars in Immunopathology, 2021
Interaction between ERAP Alleles and HLA Class I Types Support a Role of Antigen Presentation in Hodgkin Lymphoma Development.
Jiang P et al.
Cancers, 2021
Genetic contribution of endoplasmic reticulum aminopeptidase 1 polymorphisms to liver fibrosis progression in patients with HCV infection.
Vidal-Castiñeira JR et al.
Journal of Molecular Medicine (berlin, Germany), 2020
Analysis of 47 Non-MHC Ankylosing Spondylitis Susceptibility Loci Regarding Associated Variants across Whites and Han Chinese.
Zheng X et al.
The Journal of Rheumatology, 2020
Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population.
Li C et al.
Bmc Cancer, 2020
From structure to function for the characterization of ERAP1 active site in Behçet syndrome. A novel polymorphism associated with known gene variations.
Padula MC et al.
Molecular Immunology, 2020
Distribution of rs17482078 and rs27044 ERAP1 polymorphisms in a group of Italian Behçet's syndrome patients: a preliminary case-control study.
Padula MC et al.
Internal and Emergency Medicine, 2019
HPV Epitope Processing Differences Correlate with ERAP1 Allotype and Extent of CD8+ T-cell Tumor Infiltration in OPSCC.
Reeves E et al.
Cancer Immunology Research, 2019
Genotyping of Italian patients with Behçet syndrome identified two novel ERAP1 polymorphisms using sequencing-based approach.
Padula MC et al.
Human Immunology, 2019
Epistatic Interaction of ERAP1 and HLA-B*51 in Iranian Patients with Behçet's Disease.
Mahmoudi M et al.
Scientific Reports, 2018
Evaluation of ERAP1 Gene Single Nucleotide Polymorphism in Impressing the Inflammatory Cytokine Profile of Ankylosing Spondylitis Patients.
Mohammadi H et al.
Iranian Journal of Allergy, Asthma, and Immunology, 2018
Association of ERAP1 gene polymorphisms with the susceptibility to psoriasis vulgaris: A case-control study.
Fu Y et al.
Medicine, 2018
The role of polymorphic ERAP1 in autoinflammatory disease.
Reeves E et al.
Bioscience Reports, 2018
Allele-specific Alterations in the Peptidome Underlie the Joint Association of HLA-A*29:02 and Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) with Birdshot Chorioretinopathy.
Sanz-Bravo A et al.
Molecular & Cellular Proteomics : Mcp, 2018
An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes.
Paladini F et al.
Scientific Reports, 2018
Ranking the Contribution of Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphisms to Shaping the HLA-B*27 Peptidome.
Sanz-Bravo A et al.
Molecular & Cellular Proteomics : Mcp, 2018
How ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I Proteins.
López de Castro JA
Frontiers in Immunology, 2018
Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.
Dand N et al.
Human Molecular Genetics, 2017
Associations of ERAP1 coding variants and domain specific interaction with HLA-C∗06 in the early onset psoriasis patients of India.
Das A et al.
Human Immunology, 2017
Bioinformatics analysis of genetic variants of endoplasmic reticulum aminopeptidase 1 in ankylosing spondylitis.
Wang X et al.
Molecular Medicine Reports, 2017
The ERAP gene is associated with HCV chronic infection in a Chinese Han population.
Liu S et al.
Human Immunology, 2017
The Behçet's disease-associated variant of the aminopeptidase ERAP1 shapes a low-affinity HLA-B*51 peptidome by differential subpeptidome processing.
Guasp P et al.
The Journal of Biological Chemistry, 2017
Separate effects of the ankylosing spondylitis associated ERAP1 and ERAP2 aminopeptidases determine the influence of their combined phenotype on the HLA-B*27 peptidome.
Martín-Esteban A et al.
Journal of Autoimmunity, 2017
ERAP1 association with ankylosing spondylitis is attributable to common genotypes rather than rare haplotype combinations.
Roberts AR et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017
Cervical Carcinogenesis and Immune Response Gene Polymorphisms: A Review.
Mehta AM et al.
Journal of Immunology Research, 2017
A single endoplasmic reticulum aminopeptidase-1 protein allotype is a strong risk factor for Behçet's disease in HLA-B*51 carriers.
Takeuchi M et al.
Annals of the Rheumatic Diseases, 2016
Single Nucleotide Polymorphisms of the ERAP1 Gene and Risk of NSCLC: A Comparison of Genetically Distant Populations, Chinese and Caucasian.
Yao Y et al.
Archivum Immunologiae Et Therapiae Experimentalis, 2016
ERAP1 and ERAP2 Gene Variations Influence the Risk of Psoriatic Arthritis in Romanian Population.
Popa OM et al.
Archivum Immunologiae Et Therapiae Experimentalis, 2016