Associated Papers
Corilagin regulates antigen processing and presentation by directly binding to inhibit ERAP1.
Sun X et al.
International Immunopharmacology, 2025
The Genetic Background of Ankylosing Spondylitis Reveals a Distinct Overlap with Autoimmune Diseases: A Systematic Review.
Zormpa T et al.
Journal of Clinical Medicine, 2025
Defining a genetic background for bamboo spine and axial spondyloarthritis.
Özkaya ŞÇ et al.
Joint Bone Spine, 2025
Endogamy and high prevalence of deleterious mutations in India: evidence from strong founder events.
Machha P et al.
Journal of Genetics and Genomics = Yi Chuan Xue Bao, 2025
Proteogenomic Profiling of Treatment-Naïve Metastatic Malignant Melanoma.
Kuras M et al.
Cancers, 2025
A novel allosteric driver mutation of β-glucuronidase promotes head and neck squamous cell carcinoma progression through STT3B-mediated PD-L1 N-glycosylation.
Liu Z et al.
Medcomm, 2025
ERAP1 Gene Variants and Haplotypes Associated With Psoriasis Vulgaris of Han Chinese in Inner Mongolia.
Li X et al.
Molecular Genetics & Genomic Medicine, 2024
Association of a single nucleotide polymorphism (rs27434) in the ERAP1 gene with plural tissue weight.
Sasaki T et al.
Legal Medicine (tokyo, Japan), 2024
ACE Phenotyping in Human Blood and Tissues: Revelation of ACE Outliers and Sex Differences in ACE Sialylation.
Enyedi EE et al.
Biomedicines, 2024
The Role of Aminopeptidase ERAP1 in Human Pathology-A Review.
Țiburcă L et al.
Current Issues in Molecular Biology, 2024
Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties.
Georgaki G et al.
Frontiers in Immunology, 2024
Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population.
Kril I et al.
Frontiers in Immunology, 2024
A large meta-analysis identifies genes associated with anterior uveitis.
Gelfman S et al.
Nature Communications, 2023
Shedding Light on the Role of ERAP1 in Axial Spondyloarthritis.
Saad MA et al.
Cureus, 2023
Indicators of HSV1 Infection, ECM-Receptor Interaction, and Chromatin Modulation in a Nuclear Family with Schizophrenia.
Huang YC et al.
Journal of Personalized Medicine, 2023
The relationship between vitamin D receptor gene polymorphisms and ankylosing spondylitis: a systematic review, meta-analysis and trial sequential analysis.
Zhou H et al.
Rheumatology International, 2023
Single-cell genome-wide association reveals that a nonsynonymous variant in ERAP1 confers increased susceptibility to influenza virus.
Schott BH et al.
Cell Genomics, 2022
Functional ERAP1 Variants Distinctively Associate with Ankylosing Spondylitis Susceptibility under the Influence of HLA-B27 in Taiwanese.
Wang CM et al.
Cells, 2022
HLA-B27 may modulate the interaction between ERAP1 polymorphisms and smoking in ankylosing spondylitis patients.
Fernández-Torres J et al.
Molecular Biology Reports, 2022
Allele frequency spectrum of known ankylosing spondylitis associated variants in a Swedish population.
Mathioudaki A et al.
Scandinavian Journal of Rheumatology, 2022
The emerging multifunctional roles of ERAP1, ERAP2 and IRAP between antigen processing and renin-angiotensin system modulation.
Mattorre B et al.
Frontiers in Immunology, 2022
Absence of ERAP1 in B Cells Increases Susceptibility to Central Nervous System Autoimmunity, Alters B Cell Biology, and Mechanistically Explains Genetic Associations between ERAP1 and Multiple Sclerosis.
O'Connell P et al.
Journal of Immunology (baltimore, Md. : 1950), 2021
Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism.
Maben Z et al.
Nature Communications, 2021
ERAP1 binds peptide C-termini of different sequences and/or lengths by a common recognition mechanism.
Sui L et al.
Immunobiology, 2021
A First Step for the Molecular Characterization of Neurological Involvement of Behçet Syndrome: an Italian Pivotal Study.
Padula MC et al.
Journal of Molecular Neuroscience : Mn, 2021
Aberrant antigen processing and presentation: Key pathogenic factors leading to immune activation in Ankylosing spondylitis.
Nakamura A et al.
Seminars in Immunopathology, 2021
Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.
Ferreira LC et al.
Scientific Reports, 2021
The association of HLA-C and ERAP1 polymorphisms in early and late onset psoriasis and psoriatic arthritis patients of Hungary.
Képíró L et al.
Postepy Dermatologii I Alergologii, 2021
Interaction between ERAP Alleles and HLA Class I Types Support a Role of Antigen Presentation in Hodgkin Lymphoma Development.
Jiang P et al.
Cancers, 2021
Genetics and the axial spondyloarthritis spectrum.
Brown MA et al.
Rheumatology (oxford, England), 2020
Genetic contribution of endoplasmic reticulum aminopeptidase 1 polymorphisms to liver fibrosis progression in patients with HCV infection.
Vidal-Castiñeira JR et al.
Journal of Molecular Medicine (berlin, Germany), 2020
A genetic polymorphism of IL17F rs763780 associated with anti-E production in the Han Chinese population.
Chen S et al.
Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis, 2020
Genomewide Association Study of Acute Anterior Uveitis Identifies New Susceptibility Loci.
Huang XF et al.
Investigative Ophthalmology & Visual Science, 2020
Analysis of 47 Non-MHC Ankylosing Spondylitis Susceptibility Loci Regarding Associated Variants across Whites and Han Chinese.
Zheng X et al.
The Journal of Rheumatology, 2020
MHC associations of ankylosing spondylitis in East Asians are complex and involve non-HLA-B27 HLA contributions.
Wang G et al.
Arthritis Research & Therapy, 2020
From structure to function for the characterization of ERAP1 active site in Behçet syndrome. A novel polymorphism associated with known gene variations.
Padula MC et al.
Molecular Immunology, 2020
The Role of Insulin Regulated Aminopeptidase in Endocytic Trafficking and Receptor Signaling in Immune Cells.
Descamps D et al.
Frontiers in Molecular Biosciences, 2020
Distribution of rs17482078 and rs27044 ERAP1 polymorphisms in a group of Italian Behçet's syndrome patients: a preliminary case-control study.
Padula MC et al.
Internal and Emergency Medicine, 2019
HPV Epitope Processing Differences Correlate with ERAP1 Allotype and Extent of CD8+ T-cell Tumor Infiltration in OPSCC.
Reeves E et al.
Cancer Immunology Research, 2019
The genetics, structure and function of the M1 aminopeptidase oxytocinase subfamily and their therapeutic potential in immune-mediated disease.
Hanson AL et al.
Human Immunology, 2019
Endoplasmic reticulum aminopeptidase 1 polymorphism Ile276Met is associated with atopic dermatitis and affects the generation of an HLA-C associated antigenic epitope in vitro.
Niepiekło-Miniewska W et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2019
Genotyping of Italian patients with Behçet syndrome identified two novel ERAP1 polymorphisms using sequencing-based approach.
Padula MC et al.
Human Immunology, 2019
Association Study of Single Nucleotide Polymorphisms of Endoplasmic Reticulum Aminopeptidase 1 and 2 Genes in Iranian Women with Preeclampsia.
Dargahi H et al.
Iranian Journal of Public Health, 2019
Association of ERAP1 gene polymorphisms with the susceptibility to psoriasis vulgaris: A case-control study.
Fu Y et al.
Medicine, 2018
The role of polymorphic ERAP1 in autoinflammatory disease.
Reeves E et al.
Bioscience Reports, 2018
An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes.
Paladini F et al.
Scientific Reports, 2018
Ranking the Contribution of Ankylosing Spondylitis-associated Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphisms to Shaping the HLA-B*27 Peptidome.
Sanz-Bravo A et al.
Molecular & Cellular Proteomics : Mcp, 2018
Whole exome sequencing in three families segregating a pediatric case of sarcoidosis.
Calender A et al.
Bmc Medical Genomics, 2018