Varaico: Literature-Extracted Genetic Variants

Gene:ERBB2
Variant:p.P122L
Back to variants list

ERBB2

NM_004448.4:p.P122L

Associated Papers

HER2 alterations in non-small cell lung cancer (NSCLC): from biology and testing to advances in treatment modalities.

Ismail A et al.

Frontiers in Oncology, 2025

Plasma-based analysis of ERBB2 mutational status by multiplex digital PCR in a large series of patients with metastatic breast cancer.

Corné J et al.

Molecular Oncology, 2024

Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects.

Ishiyama N et al.

Cancer Research, 2023

35503682 (PubMed )
Supplement: can-21-0940_supplementary_data_suppsd.docx

ERBB family fusions are recurrent and actionable oncogenic targets across cancer types.

Schubert L et al.

Frontiers in Oncology, 2023

37168365 (PubMed )
Supplement: Table_4.xlsx › ERBB2_mutations

Poziotinib Inhibits HER2-Mutant-Driven Therapeutic Resistance and Multiorgan Metastasis in Breast Cancer.

Kalra R et al.

Cancer Research, 2022

35736563 (PubMed )
Supplement: can-21-3106_supplementary_data_suppst1.xlsx › METABRIC

Targeting HER2 genomic alterations in non-small cell lung cancer.

Zeng J et al.

Journal of the National Cancer Center, 2021

Mutational landscape and characteristics of ERBB2 in non-small cell lung cancer.

Wei XW et al.

Thoracic Cancer, 2020

Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity.

Robichaux JP et al.

Cancer Cell, 2019

Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.

Ross JS et al.

Cancer, 2018

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."