Varaico: Literature-Extracted Genetic Variants

Gene:ERBB2
Variant:p.E139G
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ERBB2

NM_004448.4:p.E139G

Associated Papers

The HER2 S310F Mutant Can Form an Active Heterodimer with the EGFR, Which Can Be Inhibited by Cetuximab but Not by Trastuzumab as well as Pertuzumab.

Shin JW et al.

Biomolecules, 2019

Clinical and pathological characterization of HER2 mutations in human breast cancer: a systematic review of the literature.

Petrelli F et al.

Breast Cancer Research and Treatment, 2017

HER2 somatic mutations are associated with poor survival in HER2-negative breast cancers.

Wang T et al.

Cancer Science, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."