Varaico: Literature-Extracted Genetic Variants

Gene:ERBB2
Variant:p.G222C
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ERBB2

NM_004448.4:p.G222C

Associated Papers

Integrating evidence from protein domains to identify cancer driver mutations.

Ostroverkhova D et al.

Protein Science : a Publication of the Protein Society, 2026

41556616 (PubMed )
Supplement: PRO-35-e70422-s002.xlsx › Table_S1

Molecular analysis of the evolutionary history of endometrial and ovarian carcinoma in Lynch syndrome.

Kauppinen AK et al.

International Journal of Cancer, 2025

40772756 (PubMed )
Supplement: IJC-157-2294-s002.xlsx › A_Blood_as_normal

Molecular landscape of ERBB2 alterations in 3000 advanced NSCLC patients.

Hong L et al.

Npj Precision Oncology, 2024

Similar genetic profile in early and late stage urothelial tract cancer.

Stormoen DR et al.

Journal of Cancer Research and Clinical Oncology, 2024

38976041 (PubMed )
Supplement: 432_2024_5850_MOESM2_ESM.xlsx › TCGA-cohort

ERBB2-Mutant Gastrointestinal Tumors Represent Heterogeneous Molecular Biology, Particularly in Microsatellite Instability, Tumor Mutation Burden, and Co-Mutated Genes: An In Silico Study.

Uchida S et al.

Current Issues in Molecular Biology, 2023

37754252 (PubMed )
Supplement: cimb-45-00468-s001.zip › Table_S1.xlsx › Sheet1

ERBB family fusions are recurrent and actionable oncogenic targets across cancer types.

Schubert L et al.

Frontiers in Oncology, 2023

37168365 (PubMed )
Supplement: Table_3.xlsx › ERBB2_mutations

Plasma Genotyping at the Time of Diagnostic Tissue Biopsy Decreases Time-to-Treatment in Patients With Advanced NSCLC-Results From a Prospective Pilot Study.

Thompson JC et al.

Jto Clinical and Research Reports, 2022

35392653 (PubMed )
Supplement: mmc3.xlsx › All_data

Associations of HER2 Mutation With Immune-Related Features and Immunotherapy Outcomes in Solid Tumors.

Wang D et al.

Frontiers in Immunology, 2022

RNA-SSNV: A Reliable Somatic Single Nucleotide Variant Identification Framework for Bulk RNA-Seq Data.

Long Q et al.

Frontiers in Genetics, 2022

35846154 (PubMed )
Supplement: Table3.XLSX › BLCA_RNA_DNA_overlap

Targeting HER2 genomic alterations in non-small cell lung cancer.

Zeng J et al.

Journal of the National Cancer Center, 2021

Analysis of targeted somatic mutations in pleomorphic carcinoma of the lung using next-generation sequencing technique.

Manabe S et al.

Thoracic Cancer, 2020

32578376 (PubMed )
Supplement: TCA-11-2262-s003.xlsx › Sheet1

Mutational landscape and characteristics of ERBB2 in non-small cell lung cancer.

Wei XW et al.

Thoracic Cancer, 2020

The Immunogenic Potential of Recurrent Cancer Drug Resistance Mutations: An In Silico Study.

Punta M et al.

Frontiers in Immunology, 2020

33133066 (PubMed )
Supplement: Table_1.xlsx › Drivers-not-HR

Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity.

Robichaux JP et al.

Cancer Cell, 2019

Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.

Loree JM et al.

Journal of the National Cancer Institute, 2018

High Frequency of Juxtamembrane Domain ERBB2 Mutation in Gastric Cancer.

Park S et al.

Cancer Genomics & Proteomics, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."