Associated Papers
Revisiting variation in the somatic mutation landscape of non-small cell lung cancer.
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Supplement: mmc1.xlsx › TableS1B.ActionableBiomarkers
Gastric cancer actionable genomic alterations across diverse populations worldwide and pharmacogenomics strategies based on precision oncology.
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Frontiers in Pharmacology, 2024
Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects.
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Supplement: can-21-0940_supplementary_data_suppsd.docx
Integrated approach to functional analysis of an ERBB2 variant of unknown significance detected by a cancer gene panel test.
Harada Y et al.
Cellular Oncology (dordrecht, Netherlands), 2022
Clinical implications of plasma ctDNA features and dynamics in gastric cancer treated with HER2-targeted therapies.
Zhang C et al.
Clinical and Translational Medicine, 2020
The HER2 S310F Mutant Can Form an Active Heterodimer with the EGFR, Which Can Be Inhibited by Cetuximab but Not by Trastuzumab as well as Pertuzumab.
Shin JW et al.
Biomolecules, 2019
Finding driver mutations in cancer: Elucidating the role of background mutational processes.
Brown AL et al.
Plos Computational Biology, 2019
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Supplement: pcbi.1006981.s010.xlsx › final_benchmark
Integrative omics analyses broaden treatment targets in human cancer.
Sengupta S et al.
Genome Medicine, 2018
30053901 (PubMed )
Supplement: 13073_2018_564_MOESM2_ESM.xlsx › 3
Impact of ERBB2 mutations on in vitro sensitivity of bladder cancer to lapatinib.
de Martino M et al.
Cancer Biology & Therapy, 2014
Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.
Greulich H et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012
Comprehensive genomic characterization defines human glioblastoma genes and core pathways.
Unknown Author
Nature, 2008
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