Varaico: Literature-Extracted Genetic Variants

Gene:ERBB2
Variant:p.Q680R
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ERBB2

NM_004448.4:p.Q680R

Associated Papers

The GigaAssay: A combined high throughput and highly accurate platform for variant classification.

Giacoletto CJ et al.

New Biotechnology, 2025

High-throughput characterization of 5886 HER2 variants identifies 112 new in cellulo gain-of-function mutations.

Giacoletto CJ et al.

Genomics, 2025

New Gain-of-Function Mutations Prioritize Mechanisms of HER2 Activation.

Giacoletto CJ et al.

Medrxiv : the Preprint Server for Health Sciences, 2025

Clinical and pathological characterization of HER2 mutations in human breast cancer: a systematic review of the literature.

Petrelli F et al.

Breast Cancer Research and Treatment, 2017

Dual Characteristics of Novel HER2 Kinase Domain Mutations in Response to HER2-Targeted Therapies in Human Breast Cancer.

Zuo WJ et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."