Varaico: Literature-Extracted Genetic Variants

Gene:ERBB2
Variant:p.G776R
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ERBB2

NM_004448.4:p.G776R

Associated Papers

First-Line Pyrotinib Combination Therapy for HER2-Mutated Advanced NSCLC: A Retrospective Cohort Analysis.

Xiang Y et al.

Current Oncology (toronto, Ont.), 2025

Clinical and structural insights into the rare but oncogenic HER2-activating missense mutations in non-small cell lung cancer: a retrospective ATLAS cohort study.

Yang G et al.

Discover Oncology, 2024

The HER2 S310F Mutant Can Form an Active Heterodimer with the EGFR, Which Can Be Inhibited by Cetuximab but Not by Trastuzumab as well as Pertuzumab.

Shin JW et al.

Biomolecules, 2019

Clinical and pathological characterization of HER2 mutations in human breast cancer: a systematic review of the literature.

Petrelli F et al.

Breast Cancer Research and Treatment, 2017

Clinical sequencing using a next-generation sequencing-based multiplex gene assay in patients with advanced solid tumors.

Kou T et al.

Cancer Science, 2017

HER2 somatic mutations are associated with poor survival in HER2-negative breast cancers.

Wang T et al.

Cancer Science, 2017

Lung adenocarcinoma harboring mutations in the ERBB2 kinase domain.

Sonobe M et al.

The Journal of Molecular Diagnostics : Jmd, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."