Varaico: Literature-Extracted Genetic Variants

Gene:ERBB2
Variant:p.G778D
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ERBB2

NM_004448.4:p.G778D

Associated Papers

An effective strategy for ligand-mediated pulldown of the HER2/HER3/NRG1β heterocomplex and cryo-EM structure determination at low sample concentrations.

Trenker R et al.

Methods in Enzymology, 2022

Structures of the HER2-HER3-NRG1β complex reveal a dynamic dimer interface.

Diwanji D et al.

Nature, 2021

Mutational activation of ErbB2 reveals a new protein kinase autoinhibition mechanism.

Fan YX et al.

The Journal of Biological Chemistry, 2008

Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex.

Xu W et al.

Nature Structural & Molecular Biology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."