Varaico: Literature-Extracted Genetic Variants

Gene:ERBB2
Variant:p.L786V
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ERBB2

NM_004448.4:p.L786V

Associated Papers

Neratinib + fulvestrant + trastuzumab for HR-positive, HER2-negative, HER2-mutant metastatic breast cancer: outcomes and biomarker analysis from the SUMMIT trial.

Jhaveri K et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2023

Mutation Profiles of Ovarian Seromucinous Borderline Tumors in Japanese Patients.

Sasamori H et al.

Current Oncology (toronto, Ont.), 2022

Targeting HER2 genomic alterations in non-small cell lung cancer.

Zeng J et al.

Journal of the National Cancer Center, 2021

Genomic profile of advanced breast cancer in circulating tumour DNA.

Kingston B et al.

Nature Communications, 2021

Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity.

Robichaux JP et al.

Cancer Cell, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."