Varaico: Literature-Extracted Genetic Variants

Gene:ERBB2
Variant:p.V842L
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ERBB2

NM_004448.4:p.V842L

Associated Papers

Enhanced computational strategies for categorizing HER2 kinase domain variants of uncertain significance through structural and functional analysis.

Loganathan T et al.

Mammalian Genome : Official Journal of the International Mammalian Genome Society, 2025

PIK3CA Mutations and Co-Mutations in Operated Non-Small Cell Lung Carcinoma.

Cokpinar S et al.

Journal of Clinical Medicine, 2024

39685930 (PubMed )
Supplement: jcm-13-07472-s001.zip › jcm-3207376-supplementary.pdf

Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects.

Ishiyama N et al.

Cancer Research, 2023

Oncogenic ERBB2 aberrations and KRAS mutations cooperate to promote pancreatic ductal adenocarcinoma progression.

Li Z et al.

Carcinogenesis, 2020

Prolonged Response to HER2-Directed Therapy in a Patient With HER2-Amplified, Rapidly Progressive Metastatic Colorectal Cancer.

Parikh A et al.

Journal of the National Comprehensive Cancer Network : Jnccn, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."