Varaico: Literature-Extracted Genetic Variants

Gene:ERBB2
Variant:p.L869Q
Back to variants list

ERBB2

NM_004448.4:p.L869Q

Associated Papers

Concurrent genomic assessment of circulating tumour cells and ctDNA to guide therapy in metastatic breast cancer.

Allsopp RC et al.

Bmc Cancer, 2025

41351070 (PubMed )
Supplement: 12885_2025_15187_MOESM1_ESM.zip › Supp_Table_1.xlsx › Sheet1

Enhanced computational strategies for categorizing HER2 kinase domain variants of uncertain significance through structural and functional analysis.

Loganathan T et al.

Mammalian Genome : Official Journal of the International Mammalian Genome Society, 2025

Landscape of drug-resistance mutations in kinase regulatory hotspots.

Kim P et al.

Briefings in Bioinformatics, 2021

Clinical and pathological characterization of HER2 mutations in human breast cancer: a systematic review of the literature.

Petrelli F et al.

Breast Cancer Research and Treatment, 2017

An Acquired HER2T798I Gatekeeper Mutation Induces Resistance to Neratinib in a Patient with HER2 Mutant-Driven Breast Cancer.

Hanker AB et al.

Cancer Discovery, 2017

ERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomas.

Deniziaut G et al.

Oncotarget, 2016

Structure-functional prediction and analysis of cancer mutation effects in protein kinases.

Dixit A et al.

Computational and Mathematical Methods in Medicine, 2014

CanDrA: cancer-specific driver missense mutation annotation with optimized features.

Mao Y et al.

Plos One, 2013

24205039 (PubMed )
Supplement: pone.0077945.s001.xls › Table_S10

Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas.

Lee JW et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2006

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."