Varaico: Literature-Extracted Genetic Variants

Gene:ERBB2
Variant:p.R897G
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ERBB2

NM_004448.4:p.R897G

Associated Papers

ERBB2/HER2 Alterations in ctDNA and Metachronous Tissues of Patients with Metastatic Urothelial Cancer.

Vandekerkhove G et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2025

Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer.

Vandekerkhove G et al.

Nature Communications, 2021

33420073 (PubMed )
Supplement: 41467_2020_20493_MOESM3_ESM.xlsx › Supplementary_Data_4

The HER2 S310F Mutant Can Form an Active Heterodimer with the EGFR, Which Can Be Inhibited by Cetuximab but Not by Trastuzumab as well as Pertuzumab.

Shin JW et al.

Biomolecules, 2019

Clinical and pathological characterization of HER2 mutations in human breast cancer: a systematic review of the literature.

Petrelli F et al.

Breast Cancer Research and Treatment, 2017

HER2 somatic mutations are associated with poor survival in HER2-negative breast cancers.

Wang T et al.

Cancer Science, 2017

Targeted genomic analysis of Müllerian adenosarcoma.

Howitt BE et al.

The Journal of Pathology, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."